Diap
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Como uma equipe de ESF pode auxiliar pacientes no climatério?
As atribuições referentes a cada profissional da ESF estão na Portaria N° 399-GM e Portaria N° 648-GM.
Com base nas Portarias, a divisão de tarefas em equipe para melhor atender as pacientes no climatério de acordo com as algumas hipóteses diagnósticas que cada pode vir a desenvolver:
Fadiga caracterizada por libido comprometid
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. O lobby dos trabalhadores no processo constituinte de 1987-88: um estudo sobre a atuação do DIAP
RESUMO O objetivo deste artigo é mostrar a influência da atuação de grupos de interesse na constitucionalização de direitos do trabalho durante o processo constituinte de 1987-88. Sustentamos que os interesses da classe trabalhadora foram articulados pelo Departamento Intersindical de Assessoria Parlamentar (DIAP), através de um projeto consensual par
Estud. hist. (Rio J.). Publicado em: 2016-12
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3. A atuação de ex-arenistas e ex-emedebistas na assembleia nacional constituinte
Qual foi o comportamento dos deputados federais remanescentes de Arena e MDB na Assembleia Nacional Constituinte? Até que ponto a análise do histórico de filiação partidária constitui-se em variável relevante para se entender o processo de tomada de decisão em plenário em votações importantes? Estas premissas são o ponto de partida para análise
Revista Brasileira de Ciências Sociais. Publicado em: 2011-10
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4. The Brazilian Congress in Mercosul foreign policy and Alca discussion, 1989/2003 / O Congresso Nacional Brasileiro na política externa do Mercosul e no debate ALCA, 1989/2003
This research analyses Brazilian Congress and its role during 1989 to 2003 concerning the foreign politics of regional integration in two arenas, the Mercosul and the FTAA discussion. Two aproaches are found in Brazilian scholar literature related to executive-legislative interacion in International Relations. The first one precribes a passive role to Congre
Publicado em: 2005
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5. IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding
The Drosophila inhibitor of apoptosis protein DIAP1 ensures cell viability by directly inhibiting caspases. In cells destined to die this IAP-mediated inhibition of caspases is overcome by IAP-antagonists. Genetic evidence indicates that IAP-antagonists are non-equivalent and function synergistically to promote apoptosis. Here we provide biochemical evidence
Oxford University Press.
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6. Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
Members of the Inhibitor of Apoptosis Protein (IAP) family are essential for cell survival in Drosophila and appear to neutralize the cell death machinery by binding to and ubiquitylating pro-apoptotic caspases. Cell death is triggered when ‘Reaper-like’ proteins bind to IAPs and liberate caspases from IAPs. We have identified the thioredoxin peroxidase
Oxford University Press.
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7. The Drosophila caspase DRONC is regulated by DIAP1
We have isolated the recently identified Drosophila caspase DRONC through its interaction with the effector caspase drICE. Ectopic expression of DRONC induces cell death in Schizosaccharomyces pombe, mammalian fibroblasts and the developing Drosophila eye. The caspase inhibitor p35 fails to rescue DRONC-induced cell death in vivo and is not cleaved by DRONC
Oxford University Press.
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8. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
Induction of apoptosis in Drosophila requires the activity of three closely linked genes, reaper, hid and grim. Here we show that the proteins encoded by reaper, hid and grim activate cell death by inhibiting the anti-apoptotic activity of the Drosophila IAP1 (diap1) protein. In a genetic modifier screen, both loss-of-function and gain-of-function alleles in
Oxford University Press.
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9. Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark
In mammals and Drosophila, apoptotic caspases are under positive control via the CED-4/Apaf-1/Dark adaptors and negative control via IAPs (inhibitor of apoptosis proteins). However, the in vivo genetic relationship between these opposing regulators is not known. In this study, we demonstrate that a dark mutation reverses catastrophic defects seen in Diap1 mu
Oxford University Press.
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10. A low-Ca2+ response operon encodes the V antigen of Yersinia pestis.
Yersinia pestis has a virulence regulon called the low-Ca2+ response that is mediated by the plasmid pCD and manifested as regulation of growth and of expression of several virulence-associated properties by Ca2+ and temperature. We used Mu dI(Ap lac) to obtain a mutation in pCD1 of Y. pestis KIM that rendered the bacteria unable to express one of these prop
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11. Multiple Apoptotic Caspase Cascades Are Required in Nonapoptotic Roles for Drosophila Spermatid Individualization
Spermatozoa are generated and mature within a germline syncytium. Differentiation of haploid syncytial spermatids into single motile sperm requires the encapsulation of each spermatid by an independent plasma membrane and the elimination of most sperm cytoplasm, a process known as individualization. Apoptosis is mediated by caspase family proteases. Many apo
Public Library of Science.
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12. A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1
Site-specific proteases play critical roles in regulating many cellular processes. To identify novel site-specific proteases, their regulators, and substrates, we have designed a general reporter system in Saccharomyces cerevisiae in which a transcription factor is linked to the intracellular domain of a transmembrane protein by protease cleavage sites. Here
The National Academy of Sciences.