Dad
Mostrando 13-24 de 434 artigos, teses e dissertações.
-
13. Comment on “Preoperative anxiety induces chronic postoperative pain by activating astrocytes in the anterior cingulate cortex region”
Resumo O Cerrado brasileiro possui diversas espécies botânicas com fins medicinais utilizadas por comunidades tradicionais e muitas dessas plantas não estão incluídas na lista do Programa de Pesquisa de Plantas Medicinais da Central de Medicamentos. O objetivo deste estudo foi a triagem fitoquímica e o bioensaio toxicológico frente ao Brine shrimp L.
Rev. Assoc. Med. Bras.. Publicado em: 2020-09
-
14. Toxicidade e fitoquímica de oito espécies usadas na medicina tradicional sul-mato-grossense, Brasil
Resumo O Cerrado brasileiro possui diversas espécies botânicas com fins medicinais utilizadas por comunidades tradicionais e muitas dessas plantas não estão incluídas na lista do Programa de Pesquisa de Plantas Medicinais da Central de Medicamentos. O objetivo deste estudo foi a triagem fitoquímica e o bioensaio toxicológico frente ao Brine shrimp L.
Braz. J. Biol.. Publicado em: 2020-09
-
15. Stability Indicating Method for Determination of Benznidazole and Its Degradation Products in Active Pharmaceutical Ingredient
Currently, treatment of Chagas disease is restricted to the use of benznidazole and nifurtimox; however, nifurtimox was temporarily suspended in some countries. Based on the limitations in pharmacological treatments, it is essential to guarantee the quality of benznidazole. Therefore, this work aimed to identify the degradation products of benznidazole and t
J. Braz. Chem. Soc.. Publicado em: 2020-06
-
16. Methodology Development and Validation of Amphotericin B Stability by HPLC-DAD
The high worldwide consumption of antibiotics and their complex impurity profiles has drawn the attention of the scientific community to the development and validation of stability methods for these drugs. Amphotericin B is an antibiotic that is a natural fermentation product of bacterium Streptomyces nodosus, used as a broad-spectrum antifungal agent, and i
J. Braz. Chem. Soc.. Publicado em: 2020-05
-
17. Iridoides, triterpenos e outros constituintes das cascas do caule e flores de Tabebuia caraiba Bignoniaceae
The trunk bark of Tabebuia caraiba Bignoniaceae was found to contain four novel iridoids, 6-O-E-p-coumaroyljioglutin D (2), 6-O-E-p-coumaroyl-3-demethyl-3-O-ethyljioglutin D (3), 6-O-E-p-coumaroyl-1-demethyl-1-O-ethyljioglutin D (4), 7-O-E-p-coumaroyljiofuranaldehyde (5), three known iridoids, including one iridoid glucoside, jioglutin D (1), rehmaglutin D (
Quím. Nova. Publicado em: 2020-04
-
18. Isolation, in vitro and in silico Evaluation of Phenylethanoid Glycoside from Arrabidaea brachypoda as Lipoxygenase Inhibitor
Lipoxygenase (LOX) plays an important role in inflammatory processes and Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) has been described as presenting anti-inflammatory activity. Therefore, the objective of this study was to develop a high-performance liquid chromatography (HPLC) procedure to directly recognize LOX inhibitor compounds in A. brachypoda c
J. Braz. Chem. Soc.. Publicado em: 2020-04
-
19. Quantification of Glyphosate and AMPA by HPLC-ICP-MS/MS and HPLC-DAD: A Comparative Study
In this work, the direct determination methodology of glyphosate and aminomethylphosphonic acid (AMPA) by high performance liquid chromatography (HPLC) using inductively coupled plasma with triple quadrupole mass spectrometer (ICP-MS/MS) was compared with the conventional method using diode array detector (HPLC-DAD). Both methods were selective, but the chro
J. Braz. Chem. Soc.. Publicado em: 2020-02
-
20. OTIMIZAÇÃO E VALIDAÇÃO DE MÉTODO BASEADO EM QuEChERS PARA DETERMINAÇÃO DE CONSERVANTES EM COSMÉTICOS POR HPLC-DAD
Parabens are widely used as preservatives in the last decades. Others preservatives such as 2-phenoxyethanol, which in addition to his good antimicrobial activity, has low allergenic potential as well others properties of interest to the cosmetic industry. In this work was developed a method for determination of methylparaben (MP), propylparaben (PP) and 2-p
Quím. Nova. Publicado em: 2020-02
-
21. CHEMICAL VARIABILITY OF Allamanda cathartica L. FLOWERS ASSESSED BY MULTIVARIATE DATA ANALYSIS
The aim of this study was to determine the chemical variability of Allamanda cathartica flowers collected in different localities of Santa Catarina State, Brazil. Extractive solutions (25 samples) were analyzed by HPLC-DAD for the qualitative and quantitative profiles of the iridoid plumieride, the flavonoid rutin as well as total flavonoid content expressed
Quím. Nova. Publicado em: 2020-02
-
22. Antimicrobial activity of propolis extract fractions against Staphylococcus spp. isolated from goat mastitis
RESUMO: O uso indiscriminado de antibióticos no tratamento de mastite caprina leva ao desenvolvimento de micro-organismos resistentes que poderão estar presentes em alimentos, colocando em risco a saúde humana. Dessa forma, a própolis surge como uma alternativa para o tratamento de doenças por possuir uma ação antimicrobiana, principalmente pela prese
Pesq. Vet. Bras.. Publicado em: 10/01/2020
-
23. Aterosclerose Carotídea Subclínica e DAD Escore Reduzido para Estratificação de Risco Cardiovascular em Pacientes HIV Positivos
Resumo Fundamento: Pacientes HIV positivos possuem 2 vezes maior risco que a população geral de apresentarem infarto e 4 vezes maior de morte súbita. Além do risco aumentado, esses indivíduos apresentam eventos cardiovasculares, em média, aproximadamente, 10 anos antes que a população geral. Objetivo: Comparar os escores Framingham e DAD reduzido p
Arq. Bras. Cardiol.. Publicado em: 2020-01
-
24. Integrative Approach Based on Leaf Spray Mass Spectrometry, HPLC-DAD-MS/MS, and NMR for Comprehensive Characterization of Isoquinoline-Derived Alkaloids in Leaves of Onychopetalum amazonicum R. E. Fr.
Onychopetalum is an Amazonian botanical genus close-related with Bocageopsis and Unonopsis, whose species are used in traditional medicine. Although these genera are widely investigated from the phytochemical viewpoint, the knowledge about Onychopetalum remains almost unexplored. In order to perform a comprehensive characterization of isoquinoline-derived al
J. Braz. Chem. Soc.. Publicado em: 2020-01