Cytoskeleton
Mostrando 13-24 de 1553 artigos, teses e dissertações.
-
13. Numeric reconstruction of 2D cellular actomyosin network from substrate displacement
Introduction: One of the fundamental structural elements of the cell is the cytoskeleton. Along with myosin, actin microfilaments are responsible for cellular contractions, and their organization may be related to pathological changes in myocardial tissue. Due to the complexity of factors involved, numerical modeling of the cytoskeleton has the potential to
Res. Biomed. Eng.. Publicado em: 27/11/2015
-
14. Effects of glucose and glutamine concentrations in human dental pulp stem cells viability. An approach for cell transplantation
PURPOSE: To evaluate microscopic behavior and viability of dental pulp stem cells under glucose and glutamine deprivation. METHODS: Human tooth tissues were minced in isolated pieces and cultured until the desired cellular proliferation for experimental phases. Cells were cultured under variations of glucose and glutamine in both serum presence and absence,
Acta Cir. Bras.. Publicado em: 2014-10
-
15. JVG9, a benzimidazole derivative, alters the surface and cytoskeleton of Trypanosoma cruzi bloodstream trypomastigotes
Trypanosoma cruzi has a particular cytoskeleton that consists of a subpellicular network of microtubules and actin microfilaments. Therefore, it is an excellent target for the development of new anti-parasitic drugs. Benzimidazole 2-carbamates, a class of well-known broad-spectrum anthelmintics, have been shown to inhibit the in vitro growth of many protozoa
Mem. Inst. Oswaldo Cruz. Publicado em: 09/09/2014
-
16. Development of experimental in vitro burn model
PURPOSE: To propose an experimental burn model in NIH-3T3 cell line.METHODS:Induction of thermal injury in cultures of mouse fibroblast - NIH-3T3- cell line and determination of cell viability by MTT and imunofluorescence.RESULTS:The heating of the Petri dish increased proportionally to the temperature of the base and the time of exposure to microwave. In th
Acta Cir. Bras.. Publicado em: 2014
-
17. Regulatory volume decrease in Leishmania mexicana: effect of anti-microtubule drugs
The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume decrease (RVD). We studied the effects of
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-02
-
18. Expressão das proteínas citoesqueléticas actina e tubulina em células osteogênicas cultivadas sobre vidro e vitrocerâmica bioativos / Expression of the cytoskeletal proteins actin and tubulin in osteogenic cells cultured on bioactive glass-based surfaces
Bioactive glasses and glass-ceramics have been successfully applied in various therapeutic strategies to promote the formation of mineralized matrix in bone defects. The exposure of these materials to biological fluids results in chemical and topographical modifications that may affect the interactions of cells with the biomaterial surface, with potential ef
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/08/2012
-
19. Inibição da migração mediada pelo gene RECK em modelo de glioma humano através de alterações no citoesqueleto e adesão focal / RECK-mediated inhibition of glioma migration with changes in cytoskeleton and focal adhesion
Gliomas são tumores altamente invasivos, resistentes aos tratamentos disponíveis atualmente e com alta taxa de mortalidade. A superexpressão de RECK na linhagem de glioma humano T98G comprometeu a capacidade das células de migrar e invadir in vitro, com rearranjo do citoesqueleto e alteração na distribuição espacial de FAK fosforilado. Entretanto, o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/05/2012
-
20. Prokaryotic cells: structural organisation of the cytoskeleton and organelles
For many years, prokaryotic cells were distinguished from eukaryotic cells based on the simplicity of their cytoplasm, in which the presence of organelles and cytoskeletal structures had not been discovered. Based on current knowledge, this review describes the complex components of the prokaryotic cell cytoskeleton, including (i) tubulin homologues composed
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-05
-
21. O papel do jaspamídeo na dinâmica do citoesqueleto de actina das células de melanoma: relação com migração e invasão. / The role of jaspamide in the actin cytoskeleton of melanoma cells: the relation between migration and invasion.
No processo de metástase os movimentos de migração e invasão tem um papel essencial e em ambos a função dos microfilamentos é de grande importância. Neste contexto, o presente trabalho buscoui analisar os efeitos da droga jaspamídeo e após a determinação das concentrações de IC50 para as linhagens HT144 e NGM foram estudados os efeitos da droga
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/11/2011
-
22. Resposta celular à infecção por Campylobacter. jejuni em embriões e explants de íleo de aves e participação do citoesqueleto e lisossomos no processo de invasão em células CACO-2
The host-pathogen interactions of C. jejuni is a little explored subject in birds and humans. Thus, this study aimed to evaluate the passage and the effects of virulent strain of C. jejuni IAL 2383 in SPF embryos of birds, the expression of cytokines and morphological changes in SPF birds explants ileum infected with C. jejuni and verify the cytoskeleton and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/09/2011
-
23. Localização genômica e subcelular dos membros da família de fosfatidilinositol quinases em Trypanosoma cruzi / Genomic and subcellular localization of the members of phosphatidylinositol kinase family in Trypanosoma cruzi
The identification of signaling molecules and the elucidation of signal transduction processes of Trypanosoma cruzi are required for understanding the host-parasite interaction and physiological processes of the parasite. However, little is yet known about signal transduction and signaling pathways that occur in the parasite, since most efforts focused on si
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011
-
24. Produção recombinante e caracterização de uma desintegrina da peçonha de Rhinocerophis alternatus (antiga Bothrops alternatus) com atividade antimetastática visando o desenvolvimento de um novo fármaco
This work presents the study of the effects of an RGD disintegrin from Rhinocerophis alternatus (ancient Bothrops alternatus) in key steps of the metastatic cascade. Disintegrins are cysteine-rich peptides, which have several biological activities related to cell-cell interaction and cell adhesion. The correct pairing of disulfide bonds exposes the adhesive
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/06/2011