Cystatin
Mostrando 25-36 de 79 artigos, teses e dissertações.
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25. Monitoring renal function: measured and estimated glomerular filtration rates - a review
Chronic kidney disease (CKD) is a world-wide public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and premature death. This finding has led to the hypothesis that earlier recognition of kidney disease and successful intervention may improve outcome. The National Kidney Foundation, through its Kidney Disease Outcomes Quality
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-06
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26. Cystatin C and renal function in pediatric kidney transplant recipients
In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-12
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27. Avaliação da cistatina C como marcador de função renal de pacientes com hipertensão arterial primária
Essential hypertension is an important risk factor for the development of chronic kidney disease. Accurate monitoring of kidney function, which is the estimation of glomerular filtration rate and determination of the presence of microalbuminuria, is mandatory in order to ensure an adequate evaluation in hypertensive patients. Cystatin C has been proposed as
Publicado em: 2009
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28. Cystatin C serum levels in term newborns along the neonatal period / Evolução dos níveis séricos de cistatina C em recém-nascidos de termo no primeiro mês de vida
INTRODUÇÃO: A cistatina C sérica apresenta boa correlação com o ritmo de filtração glomerular (RFG) e não é influenciada pela função renal materna, podendo ser um bom marcador da função renal, especialmente na 1ª semana de vida. Porém, não há valores normais definidos para o período neonatal. OBJETIVO: Determinar a evolução dos níveis s�
Publicado em: 2009
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29. Avaliação da dosagem sérica de cistatina C para detecção precoce de alterações na função do enxerto após o transplante renal / Evaluation of the serum concentration of cystatin C to early detection changes in graft function after kidney transplantation
INTRODUCTION: Cystatin C is a nonglycosylated protein that is synthesized by all nucleated cells. The present study aimed to analyze the accuracy of serum concentration of cystatin C for detecting longitudinal change in glomerular filtration rate in transplanted recipients, as well to define a better methodological strategy to perform the plasma clearance of
Publicado em: 2008
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30. Validação do método imunonefelométrico para dosagem de cistatina C, como marcador de função renal / Validation of cystatin C measurement by particle-enhanced immunonephelometry as renal function marker
A cistatina C sérica tem sido apontada como um marcador de filtração glomerular. Neste trabalho realizamos a validação de um método específico e automatizado, a imunonefelometria, mensurando os níveis séricos de cistatina C através do nefelômetro da empresa Behring (BN II). O ensaio perfaz o intervalo de referência de 0.23-7.25 mg/L, até sete ve
Publicado em: 2008
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31. Identificação e caracterização de proteinas expressas no espaço intercelular de folhas de Theobroma cacao na interação com Moniliophthora perniciosa / Identification and characterization of proteins expressed in the intercellular space of leves from Theobroma cacao infected by Moniliophthora perniciosa
The invasion of the plant apoplast is a critical phase of the infection for numerous pathogens, including the fungus M. perniciosa (Mp) that remains in the intercellular space at the parasitic stage until about 60 days. Thus, the understanding of plant defenses induced in the apoplasm and the response mechanisms that the pathogens used for bypassing these de
Publicado em: 2008
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32. Expressão recombinante da canacistatina em células de inseto.
Due to the great economic importance of sugarcane crop in Brazil, the occurrence of infections by phytopathogens leading to decreased productivity and quality remains a serious problem. As the plants have natural mechanisms of defense against the attack of fungi and insects, amongst which the inhibitors of proteases are distinguished, the use of these substa
Publicado em: 2007
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33. Cistatina C e Rifle: avanços na avaliação da função renal em pós-operatório de cirurgia cardíaca / Cystatin C and rifle: advances in assessment of the renal function in the postoperative period of cardiac surgery
A prevalência de LRA no pós-operatório (PO) de cirurgia cardíaca varia em torno de 5% a 31%, dependendo da população estudada e do critério adotado para sua definição. Os objetivos deste estudo foram classificar a função renal de pacientes em pós-operatório de cirurgia cardíaca, utilizando o sistema classificador RIFLE (R=risk, I=injury
Publicado em: 2007
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34. AvaliaÃÃo da funÃÃo renal em idosos hospitalizados: comparaÃÃo entre mÃtodos diagnÃsticos
As fÃrmulas para estimar a funÃÃo renal sÃo certamente prÃticas no contexto hospitalar, mas pouco sabemos sobre a pertinÃncia de seu uso em idosos hospitalizados com doenÃas agudas ou descompensaÃÃes de problemas crÃnicos. Esses pacientes sÃo justamente os mais sujeitos ao risco iatrogÃnico, e podem precisar de ajustes posolÃgicos em caso de ins
Publicado em: 2006
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35. Intracellular accumulation of the amyloidogenic L68Q variant of human cystatin C in NIH/3T3 cells.
AIM: To study the cellular transport of L68Q cystatin C, the cystatin variant causing amyloidosis and brain haemorrhage in patients suffering from hereditary cystatin C amyloid angiopathy (HCCAA). METHODS: Expression vectors for wild-type and L68Q cystatin C were constructed and used to transfect mouse NIH/3T3 cells. Stable cell clones were isolated after co
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36. Increased body temperature accelerates aggregation of the Leu-68-->Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy.
Hereditary cystatin C amyloid angiopathy is a dominantly inherited disorder, characterized by dementia, paralysis, and death from cerebral hemorrhage in early adult life. A variant of the cysteine proteinase inhibitor, cystatin C, is deposited as amyloid in the tissues of the patients and their spinal-fluid level of cystatin C is abnormally low. The disease-