Cyclic Amp
Mostrando 1-12 de 2761 artigos, teses e dissertações.
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1. Melatonin effects on ovarian follicular cells: a systematic review
RESUMO A melatonina é conhecida por seus efeitos no sono e no sistema reprodutivo dos mamíferos. Este último tem receptores de melatonina tipos 1 e 2, que atuam para regular, entre outras coisas, o AMP cíclico. Apesar de todos os dados da literatura, ainda não há um conhecimento sólido ou uma compreensão clara da ação do hormônio na fisiologia das
Rev. Assoc. Med. Bras.. Publicado em: 12/09/2019
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2. Dysfunctional Hyperpolarization-Activated Cyclic Nucleotide-gated Ion Channels in Cardiac Diseases
Abstract Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are reverse voltage-dependent, and their activation depends on the hyperpolarization of the membrane and may be directly or indirectly regulated by the cyclic adenosine monophosphate (cAMP) or other signal-transduction cascades. The distribution, quantity and activation states of HCN
Braz. J. Cardiovasc. Surg.. Publicado em: 2016-04
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3. Vias intracelulares da ação do Sildenafil no diabetes insipidus induzido pelo lítio / Sildenafil action in lithium-induced NDI: intracellular pathway
Patients taking lithium to treat bipolar disorder often present polyuria and urinary concentrating defect. In addition, lithium-treated animals present lower cyclic adenosine monophosphate production in response to vasopressin. Sildenafil (Sil), a phosphodiesterase 5 (PDE5) inhibitor, elevates intracellular cyclic guanosine monophosphate (cGMP) levels, leadi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/06/2012
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4. Determinação de etanol e metanol em álcool combustível e gasolina empregando métodos eletroanalíticos
In this present work two analytical procedures are presented. The first deals with the simultaneous determination of ethanol (EtOH) and methanol (MetOH) in fuel ethanol samples using Cyclic Voltammetry (CV) and the second, the determination of EtOH in fuel ethanol and gasohol using Batch Injection Analysis with Multiple Pulses Amperometric detection (BIA-MPA
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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5. Análise do gene AIP na acromegalia familial isolada / Analysis of the AIP gene in familial isolated acromegaly
Acromegaly is a rare disfigurating and insidious disease characterized by enlargement of hands, feet and skull bones due to excess of growth hormone (GH) secreted by a pituitary tumor (somatotropinoma). The majority of the cases with acromegaly is sporadic, however it may occur in association with inherited disorders as Multiple Endocrine Neoplasia type 1 (M
Publicado em: 2010
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6. Avaliação do consumo de cafeína em pacientes com Doença Renal Policística Autossômica Dominante (DRPAD) / Caffeine intake in Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients
A cafeína tem sido considerada um fator de risco para o crescimento dos cistos na Doença Renal Policística Autossômica Dominante (DRPAD) devido ao aumento de secreção de fluido e proliferação celular induzidos pelo acúmulo de adenosina monofosfato cíclico (AMPc), resultante da inibição da fosfodiesterase. O presente estudo teve como objetivos qua
Publicado em: 2010
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7. Mecanismos genômicos e não-genômicos de controle da sinalização do AMP cíclico / Genomic and non-genomic control mechanisms of the cyclic AMP signaling
A via de sinalização do AMP cíclico (AMPc) modula vários aspectos da fisiologia do músculo esquelético e da sinapse neuromuscular, como o trofismo muscular, a liberação de neurotransmissores, a expressão e a dessensibilização de proteínas sinápticas cruciais, tais como a acetilcolinesterase (AChE) e os receptores nicotínicos, além da própria
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/07/2009
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8. AvaliaÃÃo dos efeitos do inibidor de fosfodiesterase 5 sobre a ovogÃnese de camundongos
Vardenafil citrate is a potent vasodilator, with use in the treatment of patients with erectile dysfunction. Its mechanism of action is based on selective inhibition of phosphodiesterase-5 (PDE5), specific to guanosine 3â,5â-cyclic monophosphate (cGMP). The phosphodiesterases are enzymes capable of regulating the levels of cAMP (adenosine 3â,5â-cyclic mo
Publicado em: 2009
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9. Investigação do efeito vasorelaxante e caracterização eletrofisiológica dos alcalóides curina e reticulina
It was been demonstrated that curine and reticuline, induced a vasodilator effect in the rat small mesenteric arteries through inhibition of voltage-gated Ca2+ channels (VGCC). These compounds, curine and reticuline were isolated from the root barks of Chondrondendron platyphyllum and Ocotea duckei Vattimo, respectively, therefore the aim of this work was to
Publicado em: 2009
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10. Avaliação do efeito relaxante do BAY 41-2272 em detrusor isolado de coelhos / Evaluation of relaxant effect of BAY 41-2272 in rabbit isolated detrusor
Overactive bladder (OAB) is a highly prevalent condition that affects millions of people worldwide with a profound effect on quality of life. The bladder overactivity is related to spontaneous contractions of the detrusor smooth muscle causing an increase in the intravesical pressure and consequently stimulation of the micturirion reflex. Evidences suggest t
Publicado em: 2009
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11. Role of nitric oxide and the cyclic guanosine monophosphate dependent patway on the adhesive properties leucocytes of sickle cell disease patients / Ação do oxido nitrico e da via dependente de guanosina monofosfato ciclico nas propriedades adesivas de leucocitos de pacientes com anemia falciforme
Increased leukocyte adhesion to vascular endothelium contributes to vaso-occlusion in sickle cell disease (SCD). Since nitric oxide (NO) bioavailability is decreased in SCD and NO may inhibit leukocyte adhesion, we determined whether stimulation of NO-signalling pathways can decrease the adhesive properties of neutrophils from SCD individuals (SCDneu). SCDne
Publicado em: 2008
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12. Biphasic modulation of insulin receptor substrate-1 during goitrogenesis
Insulin receptor substrate-1 (IRS-1) is the main intracellular substrate for both insulin and insulin-like growth factor I (IGF-I) receptors and is critical for cell mitogenesis. Thyrotropin is able to induce thyroid cell proliferation through the cyclic AMP intracellular cascade; however, the presence of either insulin or IGF-I is required for the mitogenic
Brazilian Journal of Medical and Biological Research. Publicado em: 22/03/2007