Cryptococcus
Mostrando 13-24 de 1308 artigos, teses e dissertações.
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13. Antimicrobial, Anti-Inflammatory and Antioxidant Activities of Polyoxygenated Chalcones
It was synthesized nine polyoxygenated chalcones with a potential and safe use as antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones obtained by Claisen-Schmidt condensation were studied as antioxidant, inhibitors of human 5-lipoxygenase, antifungal, antibacterial and antibiotic resistance modifiers. Two chalcones with catecholic moieties
J. Braz. Chem. Soc.. Publicado em: 2019-02
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14. Antifungal potential of punicalagin against Cryptococcus neoformans species complex
ABSTRACT This study evaluated the antifungal activity and cytotoxicity profile of the ellagitannin punicalagin, a compound extracted from the L. pacari A. St.-Hil (Lythraceae) leaf, against Cryptococcus neoformans species complex. Minimum inhibitory concentrations (MIC) were checked using the broth microdilution method. Minimum fungicidal concentrations (MFC
Rev. Inst. Med. trop. S. Paulo. Publicado em: 22/10/2018
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15. Pneumonia por Cryptococcus neoformans em um caprino na região Sul do Brasil
RESUMO: Este relato objetiva descrever os aspectos clínicos, patológicos e moleculares de pneumonia por Cryptococcus neoformans em um caprino na região Sul do Brasil. Um caprino com histórico de transporte prolongado apresentou dispneia, secreção nasal e tosse e foi encaminhado para necropsia, análise histopatológica e micológica. Macroscopicamente
Cienc. Rural. Publicado em: 11/10/2018
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16. Peeling the onion: the outer layers of Cryptococcus neoformans
Cryptococcus neoformans is an opportunistic fungal pathogen that is ubiquitous in the environment. It causes a deadly meningitis that is responsible for over 180,000 deaths worldwide each year, including 15% of all AIDS-related deaths. The high mortality rates for this infection, even with treatment, suggest a need for improved therapy. Unique characteristic
Mem. Inst. Oswaldo Cruz. Publicado em: 07/05/2018
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17. Neglected disease, neglected populations: the fight against Cryptococcus and cryptococcosis
Mem. Inst. Oswaldo Cruz. Publicado em: 16/04/2018
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18. Variability in innate host immune responses to cryptococcosis
Cryptococcosis is an invasive fungal disease caused by Cryptococcus neoformans and the closely related species C. gattii. The severe form of the disease, cryptococcal meningitis (CM), is rapidly fatal without treatment. Although typically a disease of immunocompromised (especially HIV-positive) individuals, there is growing awareness of cryptococcal disease
Mem. Inst. Oswaldo Cruz. Publicado em: 16/04/2018
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19. Cryptococcal pathogenic mechanisms: a dangerous trip from the environment to the brain
Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious infections, most commonly of the central nervous system (CNS). C. neoformans is mainly found in the environment and acquired by inhalation. It could be metaphorically imagined that cryptococcal disease is a “journey” for the microorganism that starts in the environment, wher
Mem. Inst. Oswaldo Cruz. Publicado em: 16/04/2018
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20. The status of cryptococcosis in Latin America
Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly patients with HIV, while C. gattii generally affects otherwise health
Mem. Inst. Oswaldo Cruz. Publicado em: 05/04/2018
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21. Pneumonia fúngica em cães e gatos do sul do Brasil com sinais clínicos pulmonares
RESUMO: Pneumonia fúngica tem sido um diagnóstico diferencial em cães e gatos com sinais clínicos pulmonares, sendo também um risco de saúde pública para seus respectivos proprietários. Uma vez que uma fonte comum de exposição ambiental pode resultar em infecção, cães e gatos podem agir como sentinelas da doença para ambos, pessoas e animais. A
Pesq. Vet. Bras.. Publicado em: 2018-04
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22. Advances in Cryptococcus genomics: insights into the evolution of pathogenesis
Cryptococcus species are the causative agents of cryptococcal meningitis, a significant source of mortality in immunocompromised individuals. Initial work on the molecular epidemiology of this fungal pathogen utilized genotyping approaches to describe the genetic diversity and biogeography of two species, Cryptococcus neoformans and Cryptococcus gattii. Whol
Mem. Inst. Oswaldo Cruz. Publicado em: 19/02/2018
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23. Introns in Cryptococcus
In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regulate gene expression in response to environmental cues. I
Mem. Inst. Oswaldo Cruz. Publicado em: 19/02/2018
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24. Fluconazole levels in serum and cerebrospinal fluid according to daily dosage in patients with cryptococcosis and other fungal infections
ABSTRACT Fluconazole is extensively used for the treatment of candidiasis and cryptococcosis. Among other factors, successful treatment is related to appropriate fluconazole levels in blood and cerebrospinal fluid. In the present study, fluconazole levels were determined in 15 patients, 14 of whom had AIDS and 13 had neurocryptococcosis. The only selection c
Braz J Infect Dis. Publicado em: 2018-01