Corticotropin Releasing Hormone Receptors
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. Estudos dos genes Tbx19 e Crhr1 em cães da raça poodle com hipercortisolismo ACTH-dependente / Study of Tbx19 and Crhr1 genes in Poodle dogs with ACTH-dependent hypercortisolism
The ACTH-dependent hypercortisolism (ADH), also called Cushings disease, is one of the most commonly diagnosed endocrine diseases in dogs. The symptoms occur due to glucocorticoids excess leading to gluconeogenic, catabolic, anti-inflammatory and immunosuppressive effects in multiple organs and systems. There is a high incidence of Cushings disease in Poodle
Publicado em: 2010
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2. Study of mRNA expression of the receptors for vasopressin (AVPR1B), corticotropin releasing hormone (CRHR1) and GH secretagogues (GHSR-1a) in patients with ACTH-dependent Cushings syndrome: clinical-molecular correlation / Estudo da expressão do receptor da vasopressina (AVPR1B), do receptor do hormônio liberador de corticotrofina (CRHR1) e do receptor dos secretagogos de GH (GHSR-1a) em pacientes portadores de síndrome de Cushing ACTH-dependente: correlação clínico-molecular
INTRODUCTION: The differential diagnosis of ACTH-dependent Cushings syndrome (CS) is one of the major challenges in endocrinology, especially in view of the similar clinical and laboratorial behavior between some carcinoid tumors and Cushings disease (CD). Hence, dynamic tests of ACTH and cortisol release have been carried out with the aim to identify predic
Publicado em: 2006
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3. Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection
The release of adrenocorticotropin (ACTH) from the corticotrophs is controlled principally by vasopressin and corticotropin-releasing hormone (CRH). Oxytocin may augment the release of ACTH under certain conditions, whereas atrial natriuretic peptide acts as a corticotropin release-inhibiting factor to inhibit ACTH release by direct action on the pituitary.
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-10
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4. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH
Corticotropin-releasing hormone (CRH) is a central regulator of the hormonal stress response, causing stimulation of corticotropin and glucocorticoid secretion. CRH is also widely believed to mediate stress-induced behaviors, implying a broader, integrative role for the hormone in the psychological stress response. Mice lacking the CRH gene exhibit normal st
The National Academy of Sciences.
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5. Time-course changes of nerve growth factor, corticotropin-releasing hormone, and nitric oxide synthase isoforms and their possible role in the development of inflammatory response in experimental allergic encephalomyelitis
In this paper we report a time-course study of development of experimental allergic encephalomyelitis in Lewis rats, by monitoring neuroendocrine regulation of the hypothalamus–pituitary–adrenal axis through corticotropin-releasing hormone mRNA expression, inflammatory cellular infiltrate, macrophagic and neuronal nitric oxide synthase, nerve growth fact
The National Academy of Sciences of the USA.
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6. Angiotensin II receptors in paraventricular nucleus, subfornical organ, and pituitary gland of hypophysectomized, adrenalectomized, and vasopressin-deficient rats.
Angiotensin II has been implicated in the regulation of adrenocorticotropin and vasopressin secretion. Angiotensin II may influence the secretion of these hormones either directly at the pituitary gland or by increasing corticotropin-releasing hormone or vasopressin release from cells that are located in the paraventricular hypothalamic nucleus. Pituitary ho
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7. Expression cloning of a human corticotropin-releasing-factor receptor.
Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. We report here the cloning of a cDNA coding for a CRF receptor from a human corticotropic tumor library. The clone
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8. Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes
Sickness evokes various neural responses, one of which is activation of the hypothalamo–pituitary–adrenal (HPA) axis. This response can be induced experimentally by injection of bacterial lipopolysaccharide (LPS) or inflammatory cytokines such as IL-1. Although prostaglandins (PGs) long have been implicated in LPS-induced HPA axis activation, the mechani
The National Academy of Sciences.
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9. Involvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidation
It is well established that adrenal stress hormone-induced activation of the basolateral complex of the amygdala (BLA) influences memory consolidation. The present experiments investigated the involvement of corticotropin-releasing hormone (CRH) in the BLA in modulating memory consolidation. Bilateral infusions of the CRH receptor antagonist [9–41]-α-heli
The National Academy of Sciences.
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10. Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes
Sebaceous glands may be involved in a pathway conceptually similar to that of the hypothalamic-pituitary-adrenal (HPA) axis. Such a pathway has been described and may occur in human skin and lately in the sebaceous glands because they express neuropeptide receptors. Corticotropin-releasing hormone (CRH) is the most proximal element of the HPA axis, and it ac
The National Academy of Sciences.
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11. Immunoreactive corticotropin-releasing hormone and its binding sites in the rat ovary.
Corticotropin-releasing hormone (CRH), the principal neuropeptide regulator of pituitary ACTH secretion, is also produced at peripheral inflammatory sites, where it acts as a proinflammatory cytokine, and by the Leydig cell of the testis, where it exerts autocrine inhibition of testosterone biosynthesis. Because key ovarian functions, such as ovulation and l
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12. The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis.
Genes that are up- and down-regulated by thyroid hormone in the tail resorption program of Xenopus laevis have been isolated by a gene expression screen, sequenced, and identified in the GenBank data base. The entire program is estimated to consist of fewer than 35 up-regulated and fewer than 10 down-regulated genes; 17 and 4 of them, respectively, have been