Corpus Cavernous
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Effects of tadalafil to prevent injury on corpus cavernosum after vascular or nervous peri-prostatic bundle injury. Experimental model in rats
Abstract Purpose: To evaluate the effects of tadalafil (TD) in preventing histological alterations of the corpus cavernosum caused by isolated lesions of cavernous nerve (ILCN) and artery (ILCA) in rats. Methods: Fifty male Wistar rats were randomly assigned in five groups: G1: control; G2: bilateral ILCN; G3: bilateral ILCA; G4: ILCN+TD; G5: ILCA+TD. The
Acta Cir. Bras.. Publicado em: 28/11/2019
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2. Expression profile of endothelin receptors (ETA and ETB) and microRNAs-155 and -199 in the corpus cavernosum of rats submitted to chronic alcoholism and diabetes mellitus
Recent evidence shows that chronic ethanol consumption increases endothelin (ET)-1 induced sustained contraction of trabecular smooth muscle cells of the corpora cavernosa in corpus cavernosum of rats by a mechanism that involves increased expression of ETA and ETB receptors. Our goal was to evaluate the effects of alcohol and diabetes and their relationship
Braz J Med Biol Res. Publicado em: 01/03/2018
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3. Sesquiterpene lactones from Hedyosmum brasiliense induce in vitro relaxation of rat aorta and corpus cavernosum
Abstract Hedyosmum brasiliense Miq., Chloranthaceae, has been used in Southern Brazil as a sedative, anti-inflammatory, and aphrodisiac. In this study, endothelium-intact and endothelium-denuded rat aortic rings and strips of corpus cavernosum were used to investigate the relaxant effects of an hexane fraction of leaves of H. brasiliense and its sesquiterpen
Rev. bras. farmacogn.. Publicado em: 2016-06
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4. Penile reconstruction using mesenchymal stem cells
PURPOSE: To compare the reconstruction of corpus cavernosum segments when seeded with mesenchymal stem cells and when stem cells are infused intravenously.METHODS: Sixteen New Zealand rabbits were submitted to reconstruction of the corpus cavernosum and distributed in Group A - decellularized matrices, Group B - decellularized matrices seeded with mesenchyma
Acta Cir. Bras.. Publicado em: 2015-08
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5. Sinusoidal Constriction and Vascular Hypertrophy in the Diabetes-Induced Rabbit Penis
Objective To assess the morphological changes of penile vascular structures and the corpus cavernosum area in alloxan-induced diabetic rabbits. Materials and Methods Twenty male rabbits (2 months old) were divided into two groups with 10 rabbits each, the control group (CG) and the diabetic group (DG). The animals from DG received an intravenous injection
Int. braz j urol.. Publicado em: 2013-06
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6. Effect of Mesenchymal Stem Cells Associated to Matrixen on the Erectile Function in the Rat Model with Bilateral Cavernous Nerve Crushing Injury
ObjectivesTo evaluate the effect of mesenchymal stem cells (MSCs) and MSCs mixed with Matrixen as a cell carrier on the erectile dysfunction caused by bilateral cavernous nerve crushing injury.Materials and MethodsWhite male Sprague-Dawley rats were divided into 4 groups: sham-operated control group (n = 5), bilateral cavernous nerve crushing group (BCNC gro
Int. braz j urol.. Publicado em: 2012-12
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7. Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound
PURPOSE: The aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new NO donor of the complex nitrosil-ruthenium, named trans-[Ru(NH3)4(caffeine)(NO)]C13 (Rut-Caf) and sodium nitroprusside (SNP). MATERIALS AND METHODS: The tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (PE) (1 �
Int. braz j urol.. Publicado em: 2012-10
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8. Experimental model of human corpus cavernosum smooth muscle relaxation
PURPOSE: To describe a technique for en bloc harvesting of the corpus cavernosum, cavernous artery and urethra from transplant organ donors and contraction-relaxation experiments with corpus cavernosum smooth muscle. MATERIALS AND METHODS: The corpus cavernosum was dissected to the point of attachment with the crus penis. A 3 cm segment (corpus cavernosum an
International braz j urol. Publicado em: 2010-08
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9. IdentificaÃÃo dos mecanismos envolvidos no relaxamento da musculatura lisa cavernosa e da aorta de coelho, induzido por doadores de Ãxido nÃtrico do complexo nitrosil-rutÃnio / Identification of the involved mechanisms in the relaxation of the cavernous smooth musculatura and aorta of rabbit, induced for nitric oxide givers of the nitrosil-rutÃnio complex
Endothelial dysfunction makes 56% of patients with erectile dysfunction decline treatment with PDE-5 inhibitors. New forms of treatment are necessary for this group of patients. The present study evaluates the relaxation in vitro induced in rabbit corpus cavernosum smooth muscle and aortic rings by sodium nitroprusside (SNP) and by two new NO-donor substance
Publicado em: 2008
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10. Influencia do treinamento fisico na função eretil de ratos com deficiencia cronica de oxido nitrico / Influence of physical training in the erectile function of chronic NO-defficient rats
A disfunção erétil é definida como a incapacidade de alcançar ou manter ereção peniana adequada para a satisfação sexual, e ocorre em graus variáveis prejudicando a qualidade de vida do homem. A disfunção erétil está associada a fatores de risco como doenças cardiovasculares, hipertensão arterial, diabetes mellitus, hipercolesterolemia, envel
Publicado em: 2008
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11. Cavernous body reduction in four patients with erectile dysfunction due to insufficient venous occlusion and a deficit of elastic fibers in the tunica albugínea
INTRODUCTION: The corpora cavernosa are cylindrical vessels containing fluid under pressure. Thus, if cavernous wall resistance decreases, the radius increases and internal pressure decreases (LaPlace's law). We reasoned that if we decrease the corpus cavernosum radius, by excising a strip from each tunica albuginea, intracavernous pressure would increase du
International braz j urol. Publicado em: 2007-12
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12. Avaliação in vitro e in vivo dos efeitos do ativador da guanilil ciclase soluvel BAY 41-2272 na ereção peniana / In vitro and in vivo effects of the soluble guanilyl cyclase BAY 41-2272 on penile erection
Penile erection is a physiologic event that includes psychic, neural and vascular mechanisms and involves the interaction of smooth muscle neural stimulation and releasing of relaxant and contractile agents from endothelium. The nitric oxide (NO) - soluble guanilyl cyclase (sGC) - cGMP system is the most significant and efficient mechanism of penile erection
Publicado em: 2006