Corneal Neovascularization
Mostrando 1-12 de 30 artigos, teses e dissertações.
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1. Comparison of the inhibitory effect of topical cyclosporine A 0.1% and topical anti-VEGF application in an experimental model of corneal neovascularization
RESUMO Objetivo: Comparar os efeitos da ciclosporina tópica 0,1% e do bevacizumabe na neovascularização da córnea produzida experimentalmente em um modelo com ratos. Métodos: Trinta ratos Sprague-Dawley adultos foram usados neste estudo experimental. A córnea central dos ratos foi cauterizada quimicamente. Os ratos foram distribuídos aleatoriamente
Arquivos Brasileiros de Oftalmologia. Publicado em: 2022
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2. Corneal angiogenesis based on different protocols of alkaline cauterization in murine models
Abstract Purpose: To establish and compare protocols of alkaline cauterization for inducing corneal angiogenesis in murine models. Methods: Twenty-four adult Wistar rats were distributed into four groups (G1, G2, G3, and G4). The right eye cornea from each rat was cauterized using filter paper (3 mm), soaked in a solution of silver and potassium nitrates (
Acta Cir. Bras.. Publicado em: 2017-08
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3. Biocompatibility of Ferrara intracorneal ring segment with and without chondroitin sulfate coating: clinical and histopathological evaluation in rabbits
PURPOSE: To investigate and compare the biocompatibility of two types of Ferrara intracorneal ring segment: with and without chondroitin sulfate coating by clinical and histopathological evaluation. METHODS: A randomized experimental study was carried out on thirty right-eye corneas from 30 Norfolk albino rabbits allocated into two experimental groups: Group
Acta Cir. Bras.. Publicado em: 2013-09
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4. The effect of subconjunctival bevacizumab on corneal neovascularization, inflammation and re-epithelization in a rabbit model
PURPOSE: To evaluate the use of subconjunctival bevacizumab on corneal neovascularization in an experimental rabbit model for its effect on vessel extension, inflammation, and corneal epithelialization. METHODS: In this prospective, randomized, blinded, experimental study, 20 rabbits were submitted to a chemical trauma with sodium hydroxide and subsequently
Clinics. Publicado em: 2011
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5. In vivo quantification of corneal angiogenesis using digital image processing / QuantificaÃÃo de angiogÃnese corneana in vivo atravÃs de processamento de imagens digitais
Um programa de computador foi desenvolvido especificamente para a segmentaÃÃo e quantificaÃÃo de angiogÃnese corneana em imagens digitais capturadas in vivo. O propÃsito foi estabelecer um mÃtodo automÃtico para quantificar, de forma rÃpida, objetiva e acurada, a progressÃo temporal da resposta angiogÃnica. Desenvolveu-se ainda um modelo de angiog
Publicado em: 2006
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6. Comparison of two surgical techniques for repairing of deep corneanas injuries in dogs / Comparação de duas técnicas cirúrgicas para reparação de lesões corneanas profundas em cães
Two surgical techniques were compared for yhe reparation of deep corneal lesions in dogs the flap from the upper bulbar conjunctiva and the superficial keratectomy (homologous transplant) Tem dog of both sexes with no defined breeds were used Considered healthy after a period of adaptation profylaxis and clinical evaluation the dogs were separated into two g
Publicado em: 2005
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7. Estudo comparativo entre a ceratoplastia lamelar em cães utilizando membranas amniótica e alantoamniótica alógenas preservadas em glicerina: avaliação clínica e morfológica / Comparative study between lamellar keratoplasty using allogenous glicerin-preserved amniotic and alantoamniotic membranes in dogs: clinical and morphological evaluation
Ulcerative ceratitis is one of the most frequent ocular diseases in dogs and it requires prompt surgical and clinical therapy. In this context, surgical treatment using biological membrane implants is a benefic option. In this study alogenous 98% glycerin-preserved amniotic (MA) and alantoamniotic (MAAM) membranes were implanted on twenty corneas from dogs p
Publicado em: 2003
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8. Trehalose 6,6′-Dimycolate (Cord Factor) of Mycobacterium tuberculosis Induces Corneal Angiogenesis in Rats
Neovascularization or angiogenesis is required for the progression of chronic inflammation. The mechanism of inflammatory neovascularization in tuberculosis remains unknown. Trehalose 6,6′-dimycolate (TDM) purified from Mycobacterium tuberculosis was injected into rat corneas. TDM challenge provoked a local granulomatous response in association with neovas
American Society for Microbiology.
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9. Genetic loci that control the size of laser-induced choroidal neovascularization
Angiogenesis is controlled by a balance between stimulators and inhibitors. We propose that the balance, as well as the general sensitivity of the endothelium to these factors, varies from individual to individual. Indeed, we have found that individual mouse strains have dramatically different responses to growth factor-induced neovascularization. Quantitati
The Federation of American Societies for Experimental Biology.
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10. Corneal neovascularization treated with argon laser.
The argon laser set at 50 mum, 100-150 mW, o-2 s occluded corneal blood vessels in pigmented Dutch rabbits provided the corneal responsible for inducing vascularization was inactive. After arterial treatment with the argon laser retrograde flow in untreated veins was demonstrated by fluorescein angiography. Therefore all corneal new vessels should be treated
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11. Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.
To investigate the effects of D-penicillamine (D-Pen) on angiogenesis, we have studied the effects of this drug on in vitro proliferation of human endothelial cells (EC) and in vivo corneal neovascularization. D-Pen, in the presence of copper sulfate, suppressed tritiated thymidine ([3H]TdR) incorporation into EC in a dose-dependent manner. Significant inhib
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12. Ocular Lesions Induced by the Trachoma Agent in Rabbits
Injection of the T'ang strain of trachoma agent into the anterior chamber of the rabbit eye caused corneal opacity, characteristic microscopic lesions of the corneal endothelium, varying degrees of neovascularization of the cornea, and uveitis. These ocular changes were agent-specific. The experimental data showed that the microorganism developed in the ocul