Estudo comparativo entre a ceratoplastia lamelar em cães utilizando membranas amniótica e alantoamniótica alógenas preservadas em glicerina: avaliação clínica e morfológica / Comparative study between lamellar keratoplasty using allogenous glicerin-preserved amniotic and alantoamniotic membranes in dogs: clinical and morphological evaluation
AUTOR(ES)
Mirian Siliane Batista de Souza
DATA DE PUBLICAÇÃO
2003
RESUMO
Ulcerative ceratitis is one of the most frequent ocular diseases in dogs and it requires prompt surgical and clinical therapy. In this context, surgical treatment using biological membrane implants is a benefic option. In this study alogenous 98% glycerin-preserved amniotic (MA) and alantoamniotic (MAAM) membranes were implanted on twenty corneas from dogs previously submitted to superficial lamellar keratectomy. Clinical, ophthalmologic and histological parameters were investigated. The animals were divided in two groups and pos-operative corneal histological evaluation was taken on days 2, 7, 15, 30 and 60. Photophobia, blefarospasm, different types and severity of ocular secretion, corneal edema and neovascularization and corneal transparency at the implant site. Ocular examination revealed mild to severe photophobia and blefarospasm, moderate mucous secretion was the most frequent. Corneal edema was mild in the MA group and mild to moderate in the MAAM group. From the 15th pos-operative day neovascularization was more pronounced for both groups. Based on the histological findings the groups showed similar evolution and the healing process was found to be within normal parameters for the corneal tissue. We concluded that in dogs 98% glycerin-preserved MA and MAAM applied to keratoplasty do not differ among the parameters evaluated. Both membranes are equally effective as allogenous biological membrane for the repair of corneal defects.
ASSUNTO(S)
fetal membranes cornea enxertos em animais graft membranas fetais cães dogs córnea
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