Concanavalin A
Mostrando 1-12 de 1200 artigos, teses e dissertações.
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1. Magnetic Parkia pendula seed gum as matrix for Concanavalin A lectin immobilization and its application in affinity purification
O presente trabalho objetivou magnetizar a goma de sementes de Parkia pendula e demonstrar seu uso como matriz para imobilização covalente da lectina Concanavalina A. O composto foi aplicado em purificação de glicoconjugados por afinidade. Sementes de Parkia pendula foram hidratadas e a goma do sobrenadante foi precipitada, lavada com etanol e seca. A go
An. Acad. Bras. Ciênc.. Publicado em: 15/08/2014
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2. Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A
Immune response plays an important role in the development of hepatic fibrosis. In the present study, we investigated the effects of quercetin on hepatitis and hepatic fibrosis induced by immunological mechanism. In the acute hepatitis model, quercetin (2.5 mg/kg) was injected iv into mice 30 min after concanavalin A (Con A) challenge. Mice were sacrificed 4
Braz J Med Biol Res. Publicado em: 24/06/2014
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3. Interleukin-10-dependent down-regulation of interferon-gamma response to Leishmania by Mycobacterium leprae antigens during the clinical course of a coinfection
We have described a case of a patient with an intriguing association of mucocutaneous leishmaniasis with lepromatous leprosy, two opposite polar forms of these spectral diseases. In the present follow-up study, we investigated the effect of the addition of Mycobacterium leprae antigens on interferon-gamma (IFN-γ) production in Leishmania antigen-stimulated
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-07
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4. Interferon-gamma and interleukin-10 production by mononuclear cells from patients with advanced head and neck cancer
OBJECTIVE: This study aims to evaluate the production of interferon-gamma and interleukin-10 by stimulated peripheral blood mononuclear cells isolated from patients with supraglottic laryngeal cancer before and after surgical treatment. METHODS: Fourteen patients with advanced supraglottic laryngeal cancer were studied. Cultures of peripheral blood mononucle
Clinics. Publicado em: 2012
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5. Dynamics of immunosuppression in hamsters with experimental visceral leishmaniasis
Immunosuppression has been reported to occur during active visceral leishmaniasis and some factors such as the cytokine profile may be involved in this process. In the mouse model of cutaneous leishmaniasis using Leishmania (Leishmania) major, the Th1 response is related to protection while the Th2 response is related to disease progression. However, in hams
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-07
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6. Obtenção e caracterização de frações purificadas de saponinas de chenopodium quinoa e avaliação da formação de complexos do tipo iscom : atividades biológicas das frações e dos complexos formados
Chenopodium quinoa (quinoa) seeds are a rich protein source and well-known for their high saponin content. Chemically, quinoa saponins are triterpene glycosides being phytolaccagenic, hederagenin, oleanolic and serjanic acids the most common aglycones found in seeds. Its immunoadjuvant properties have been examined and the results obtained were conflicting.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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7. Concanavalina-A aumenta a produção de TNF-a, a atividade de receptores de manose e a capacidade de destruir Candida por macrófagos peritoneais
Recognition of Candida albicans by Toll-like receptors and lectin receptors on the phagocytic cells activates intracellular signaling pathways that trigger production of proinflammatory cytokines that are critical for host defence. Th1-response provide control of fungal infectivity by increasing the expression of receptors that acts as sensors for infection
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2010
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8. Decreased production of TNF-alpha by lymph node cells indicates experimental autoimmune encephalomyelitis remission in Lewis rats
Experimental autoimmune encephalomyelitis (EAE) is mediated by CD4+ Th1 cells that mainly secrete IFN-γ and TNF-α, important cytokines in the pathophysiology of the disease. Spontaneous remission is, in part, attributed to the down regulation of IFN-γ and TNF-α by TGF-β. In the current paper, we compared weight, histopathology and immunological paramete
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-05
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9. Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasite
Publicado em: 2010
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10. Characterization and application of thin film of carboxymehtylcellulose acetate butyrate / Caracterização e aplicação de filmes finos de acetato butirato carboximetil celulose
The effect of ethyl acetate and acetone on the solution behavior of cellulose acetate butyrate (CAB) and carboxymehtylcellulose acetate butyrate (CMCAB) and on the characteristics of films obtained either by spin coating or adsorption was investigated. Viscosity and small angle X-ray scattering (SAXS) measurements showed that ethyl acetate is a better solven
Publicado em: 2009
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11. Carcinoma ductal invasivo mamÃrio esporÃdico: uma abordagem histoquÃmica e imunohistiquÃmica
Breast cancer is the most frequent neoplasia and the main cause of cancer death in women worldwide. Among the several types of mammary gland neoplasia Invasive Ductal Carcinoma (IDC) represents 65% to 80% of all carcinomas. The major problem concerning this neoplasia is the great genotypic and phenotypic heterogeneity. This feature explains the increasing se
Publicado em: 2009
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12. Reatividade de anticorpos IgE, IgG1 e IgG4 a frações glicopeptídicas de Dermatophagoides pteronyssinus em indivíduos alérgicos e não alérgicos
Ácaros da poeira domiciliar, como Dermatophagoides pteronyssinus (Dp) são importantes fontes de alérgenos envolvidos na sensibilização de indivíduos geneticamente predispostos. Vários alérgenos são constituídos de glicoconjugados, que apresentam afinidade com lectinas, como a Concanavalina A (ConA). O objetivo deste estudo foi avaliar a reatividade
Publicado em: 2009