Cellular Adhesion Molecules
Mostrando 13-24 de 149 artigos, teses e dissertações.
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13. Analise de possiveis mecanismos e consequencias funcionais da expressão de galectina-3 em celulas de glioma expostas a condições hipoxicas / Analysis of possible mechanisms and functional consequences of galectin-3 expression in glioma cells exposed to hypoxia
Gliomas are primary Central Nervous System tumors. Among them, glioblastomas are the most common clinical forms and have the worst prognosis. In an attempt to understand glioma biology, the NG97 cell line was established. This cell line presents glioblastoma s characteristics, showing nuclear atipia and high growth rate. Recently, it was discovered that this
Publicado em: 2009
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14. Condrogenese a partir de celulas Mesenquimais do cordão umbilical humano estimuladas com IGF-1, TGF- beta 3, BMP-6 e BMP-2 em sistema de cultura monolayer e micromass / Chondrogenesis from Human Umbilical Cord Blood Mesenchymal Cells stimulated with TGF-beta3, IGF-1, BMP-2 and BMP-6
O sangue do cordão umbilical contem células tronco mesenquimais (CTM) indiferenciadas que tem potencial condrogênico e podem ser usadas para reparo de lesão articular. Durante o processo de condrogênese, a atuação de fatores de crescimento ainda não está totalmente elucidada. Este estudo teve como objetivo avaliar a formação de condrócitos, matri
Publicado em: 2009
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15. Primary bone lymphomas : comparison of the immunoexpression of apoptosis related proteins and adhesion molecules with nodal lymphomas and lymphomas metastatic to bone / Linfomas osseos primarios : estudo comparativo com linfomas nodais e linfomas osseos metastaticos quanto a imunoexpressão de proteinas relacionadas a apoptose, regulação do ciclo celular e adesão celular
The incidence of extranodal lymphomas is increasing in the last decades. Around 20 to 40% of B-cell non-Hodgkin lymphomas (NHL) arise outside the lymph nodes and may present distinct biological behavior, as compared to the corresponding nodal counterpart of similar histological grade. The heterogeneity of large B-cell lymphomas (LBCL) has been matter of vari
Publicado em: 2008
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16. Estudo da inibição do oxido nitrico sobre funções de eosinofilos humanos estimulados com eotaxina e RANTES in vitro / Study of nitric oxide inhibition in human eosinophil functions stimulated in vitro with eotaxin and RANTES
Eosinophils participate in the pathogenesis of many inflammatory diseases, including parasitic infections and allergic diseases. Of the allergic diseases, asthma is characterized by eosinophilia. Currently, asthma affects 300 million people in world, and is an important public health problem. Asthma is an inflammatory chronic disease that involves interactio
Publicado em: 2008
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17. Estudo dos mecanismos de ação da hidroquinona e fenol sobre o recrutamento leucocitário em respostas inflamatórias / Study of mechanisms of action of hydroquinone and phenol on leukocyte recruitment in inflammatory response
Hydroquinone (HQ) is one of the metabolites of benzene responsible for the toxic effects of exposure to solvent, as well as being part of the diet, medicines, tobacco and polluting the environment. Considering the immunotoxicity of this substance, our laboratory has investigated the role of exposure to HQ by prolonged period of time on acute inflammatory res
Publicado em: 2008
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18. Molecular study of cellular adhesion genes in bladder cancer / Estudo molecular de genes envolvidos com adesão celular em câncer de bexiga
Introduction: Bladder cancer is the fifth neoplasm in Western countries, whose occurrence is 336,000 new cases annually, and also being responsible for 132,000 deaths in the worldwide. The incidence of bladder tumors in Brazil were 7,550 cases in 1999, representing 2,8% of overall diagnosed cancer in both gender. One of the main therapeutic challenges is ide
Publicado em: 2007
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19. Genes differentially expressed in topic endometrium and endometriotic lesions. / Expressão gênica diferencial em tecido endometrial tópico e lesões endometrióticas
Gestational losses can be determined by a number of factors including endometriosis, a common gynecological disease characterized by endometrial tissue found outside the uterine cavity. The main symptoms of the disease involve dysmenorrhea, dyspaneuria, chronic pelvic pain and menstrual irregularities, besides fertility problems. Endometriotic lesions are mo
Publicado em: 2007
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20. Expressão imuno-histoquímica da e-caderina e da ß-catenina em carcinoma epidermóide oral com e sem metástase nodal
The adhesion molecules E-cadherin and β-catenin have been studied as possible markers to distinguish carcinomas with and without metastatic potential. The objective of this research was to study the imunohistochemistry expression of the E-cadherin and β-catenin in oral squamous cell carcinoma (OSCC), aiming to contribute for the better understandin
Publicado em: 2007
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21. Idiopathic interstitial pneumonias : of the pathogenesis and remodeling to anatomic-physician-radiological determinatives of prognostic and survival with emphasis to the vascular component / "Pneumonias intersticiais idiopáticas: da patogênese e do remodelamento aos determinantes anátomo-clínico-radiológicos de prognóstico e sobrevida com ênfase ao componente vascular"
Studied for morphology, morphometry and immunohischemistry the vascular (adhesion molecules), epithelial (adhesion molecules) and interstitial (collagen V and immune cells) remodeling in the three major types of idiopathic interstitial pneumonias: in 62 cases of IPF, 22 cases of NSIP, and 25 cases of AIP. The impact of these alterations was evaluated in the
Publicado em: 2006
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22. Polissacarídeos sulfatados de interesse farmacológico no camarão litopenaeus schimitti
Sulfated Polysaccharides with unique chemical structures and important biological activities has been found in a diversity of sea invertebrates. For that, to exist a huger interest on the biotechnology field in the research theses sulfated compounds isolated from sea organisms. Despite the privileged brazilian position for these compounds attainment, there a
Publicado em: 2006
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23. Expressão imuno-histoquímica das integrinas α2ß1, α3ß1, e α5ß1, em mucosa oral normal, hiperplasia fibroepitelial inflamatória oral e displasia epitelial oral
The objective of this study was perform by the streptoavidin-biotin technique an immunohistochemical analysis of α2β1, α3β1e α5β1 integrins in 11 normal oral mucosa (NOM), 16 oral inflammatory fibroepithelial hyperplasia (OIFH) and 25 oral epithelial dysplasia (OED) (16 mild, 2 moderates and 7 severe), to determine if exists qua
Publicado em: 2006
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24. PRECONDITIONING OF ORGAN DONORS WITH LOW LEVELS OF CARBON MONOXIDE REDUCES GRAFT IMMUNOGENICITY AND IMPROVES LONGTERM ALLOGRAFT FUNCTION
Background: Chronic rejection remains the major obstacle for successful transplantation, and to date there is no effective treatment. Events occurring prior to organ transplantation such as brain death, harvesting procedure, and ischemia-reperfusion injury lead to unspecific inflammatory damages danger signals - that increase graft immunogenicity and reduce
Publicado em: 2005