Cell Generation
Mostrando 1-12 de 2957 artigos, teses e dissertações.
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1. Omega 3 fatty acids - Potential modulators for oxidative stress and inflammation in the management of sickle cell disease
Abstract Objective Sickle cell disease is characterized by clinical complications resulting in vaso-occlusive crisis with prominent attributes of oxidative stress, inflammation, and pain. Inflammation is an integral part of this disease which further exacerbates the pain during a crisis. Omega-3 fatty acids are known to possess anti-inflammatory and anti-ag
Jornal de Pediatria. Publicado em: 2022
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2. Smudge cells percentage on blood smear is a reliable prognostic marker in chronic lymphocytic leukemia
Abstract Objective We evaluated the relevance of using the smudge cell percentage in the blood smear as a prognostic marker in CLL. Methods In this prospective study, 42 untreated Senegalese patients with CLL were enrolled. The diagnosis was established, based on the peripheral blood count and flow cytometry using the Matutes score. Cytogenetic aberrations
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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3. Molecular mechanism of benign biliary stricture inhibition by rosiglitazone-activated peroxisome proliferator-activated receptor gamma
SUMMARY OBJECTIVE: The aim of this study was to investigate whether rosiglitazone-activated peroxisome proliferator-activated receptor gamma can inhibit the occurrence of benign biliary stricture and further elucidate the relevant molecular signaling mechanism. METHODS: The primary cultured rat biliary fibroblasts following experiments were performed using
Revista da Associação Médica Brasileira. Publicado em: 2022
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4. Generation of hematopoietic stem/progenitor cells with sickle cell mutation from induced pluripotent stem cell in serum-free system
ABSTRACT Introduction Sickle cell disease (SCD) is a monogenic disease and it is estimated that 300,000 infants are born annually with it. Most treatments available are only palliative, whereas the allogeneic hematopoietic stem cell transplantation offers the only potential cure for SCD. Objective Generation of human autologous cells, when coupled with ind
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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5. Using static, kinetic and metal mobility procedures to evaluate possibilities of coal waste land disposal at Moatize Mine, Mozambique
Abstract Coal mine waste rocks produced during mining and beneficiation can affect the environment due to land degradation and acid mine drainage generation. However, proper characterization and treatment of mineral processing wastes creates options for safe disposal, enhancing the environmental performance. The aim of this study was to use static and kineti
REM, Int. Eng. J.. Publicado em: 2020-12
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6. Investigation of MHC gamma block C4A and C4B polymorphisms in unrelated hematopoietic stem cell transplantation
ABSTRACT Background: Immunological life-threatening complications frequently occur in post-hematopoietic stem cell transplantation (HSCT), despite matching recipient and donor (R/D) pairs for classical human leukocyte antigens (HLA). Studies have shown that R/D non-HLA disparities within the major histocompatibility complex (MHC) are associated with adverse
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
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7. Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies
ABSTRACT Introduction: Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19 + B-cell malignancies in numerous clinical trials. The CAR molecule, which recognizes cell-surface tumor-associated antigen independently of human leukocyte antigen (HLA), is composed by
Hematol., Transfus. Cell Ther.. Publicado em: 2020-06
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8. Organizing pneumonia in a patient with hodgkin's lymphoma and large B cell lymphoma: a rare association
ABSTRACT Toxoplasmosis is a zoonotic infection caused by the protozoan parasite Toxoplasma gondii. The infection is widely disseminated in the human population and is usually benign or asymptomatic. Systemic T. gondii infection presents risks for pregnant women and AIDS patients. Although rare, T. gondii can cause outbreaks in urban centers. The origin of th
Hematol., Transfus. Cell Ther.. Publicado em: 2020-06
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9. Epidemiological, clinical and immune factors that influence the persistence of antiphospholipid antibodies in leprosy
Abstract Introduction: Antiphospholipid antibodies (aPL) are described in individuals with leprosy without the clinical features of antiphospholipid antibody syndrome (APS), a condition involving thromboembolic phenomena. We have described the persistence of these antibodies for over 5 years in patients with leprosy after specific treatment. Objectives: To
Adv. rheumatol.. Publicado em: 09/12/2019
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10. In vitro generation of human monocyte-derived dendritic cells methodological aspects in a comprehensive review
Abstract: Dendritic cells (DCs) initiate and shape both innate and adaptive immune responses. They are specialized in antigen presentation to naive T cells, thereby orchestrating the T cell immune responses. Human peripheral blood and tissues contain several subsets of phenotypically and functionally distinct DCs, which promote interactions between the exter
An. Acad. Bras. Ciênc.. Publicado em: 28/11/2019
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11. Photovoltaic Cell Temperature Estimation for a Grid-Connect Photovoltaic Systems in Curitiba
Abstract The photovoltaic solar energy has been growing in installed capacity worldwide year by year, and Brazil has also been investing in this renewable source of energy generation. The conversion of light into electrical energy occurs in the photovoltaic cells, which are sensitive to the increase of the temperature. A considerable amount of the energy in
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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12. KINETIC STUDIES OF HYDROLYSIS REACTION OF NaBH4 WITH γ-Al2O3 NANOPARTICLES AS CATALYST PROMOTER AND CoCl2 AS CATALYST
Abstract Solid-state hydrogen storage is of considerable concern as a potential hydrogen source for portable fuel cell applications. This study mainly focuses on kinetics of NaBH4/Al2O3 nanoparticles (20 nm)/H2O system with CoCl2 as catalyst and the factors that affect the hydrogen generation rate (HGR). It is observed that the reaction rate increases consid
Braz. J. Chem. Eng.. Publicado em: 30/09/2019