Caveola
Mostrando 1-12 de 25 artigos, teses e dissertações.
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1. Caracterização das proteínas caveolinas -1 e -2 na placenta de conceptos bovinos clonados transgênicos
RESUMO:A utilização da transgenia com a proteína fluorescente verde (GFP) como marcador de células de origem fetal nas placentas de clones bovinos servirá de modelo inédito para estudo morfofisiológico e imunológico da interação materno-fetal, visto que possibilitará o seu mapeamento, diferenciando as células fetais das maternas. Tal modelo terá
Pesq. Vet. Bras.. Publicado em: 2015-05
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2. Efeito dos oxisteróis na sinalização através de cavéolas e sua relevância na aterosclerose / Effect of oxysterols in cell signaling through caveolae and its relevance to atherosclerosis
Oxisteróis (por exemplo, 7hidroxicolesterol) são gerados por modificações oxidativas que ocorrem na molécula de colesterol. Podem ser encontrados em elevados níveis plasmáticos em pacientes com aterosclerose e como componentes da placa aterosclerótica. Considerando que o colesterol é o principal componente da cavéola (domínios específicos da memb
Publicado em: 2011
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3. Interação do cininogênio humano de alta massa molecular com a superfície celular: envolvimento dos processos de endocitose e proteólise / High molecular weight human kininogen interact with cell surface: Involvement endocytosis and proteolysis process
A angiogênese e a hemostasia estão entre as mais consistentes respostas do hospedeiro associadas ao câncer, e essas duas vias interrelacionam-se, com a coagulação sanguínea e a fibrinólise influenciando a angiogênese tumoral diretamente e contribuindo com o crescimento do tumor. O fato dos tumores serem dependentes do suprimento sanguíneo tem inspir
Publicado em: 2010
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4. Efeitos celulares do óxido nítrico em aorta de ratos hipertensos renais / Cellular effects of the nitric oxide in rat aorta from renal hypertensive rats
O relaxamento vascular induzido pelo óxido nítrico (NO) está prejudicado em aorta de ratos hipertensos renais (2R-1C). A nossa hipótese é de que o menor efeito do NO na aorta de ratos 2R-1C pode estar relacionada com a maior degradação do NO e/ou modificação das cavéolas no músculo liso vascular (MLV), considerando que o NO pode ser degradado rapi
Publicado em: 2008
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5. Placental erytrophagocytosis in water buffalo (Bubalus bubalis bubalis - Simpson, 1945) / Eritrofagocitose placentária em búfalas (Bubalus bubalis bubalis - Simpson, 1945)
A função da eritrofagocitose observada após o extravasamento de sangue na interface materno-fetal é indefinida em várias espécies, incluindo o búfalo. Na ovelha, este processo foi muito estudado, e ocorre na zona arcada do placentônio (topos dos septos maternos e base dos vilos fetais), região onde o processo é realizado pelo trofoblasto. É possí
Publicado em: 2004
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6. Intersectin-2L Regulates Caveola Endocytosis Secondary to Cdc42-mediated Actin Polymerization*
Here we addressed the role of intersectin-2L (ITSN-2L), a guanine nucleotide exchange factor for the Rho GTPase Cdc42, in the mechanism of caveola endocytosis in endothelial cells (ECs). Immunoprecipitation and co-localization studies showed that ITSN-2L associates with members of the Cdc42-WASp-Arp2/3 actin polymerization pathway. Expression of Dbl homology
American Society for Biochemistry and Molecular Biology.
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7. Association of the Caveola Vesicular System with Cellular Entry by Filoviruses
The filoviruses Ebola Zaire virus and Marburg virus are believed to infect target cells through endocytic vesicles, but the details of this pathway are unknown. We used a pseudotyping strategy to investigate the cell biology of filovirus entry. We observed that specific inhibitors of the caveola system, including cholesterol-sequestering drugs and phorbol es
American Society for Microbiology.
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8. Early Steps of Polyomavirus Entry into Cells
The mechanism by which murine polyomavirus penetrates cells and arrives at the nucleus, the site of viral replication, is not well understood. Simian virus 40 and JC virus, two closely related members of the polyomavirus subfamily, use caveola- and clathrin-mediated uptake pathways for entry, respectively. The data presented here indicate that compounds that
American Society for Microbiology.
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9. Cell Penetration and Trafficking of Polyomavirus
The murine polyomavirus (Py) enters mouse fibroblasts and kidney epithelial cells via an endocytic pathway that is caveola-independent (as well as clathrin-independent). In contrast, uptake of simian virus 40 into the same cells is dependent on caveola. Following the initial uptake of Py, both microtubules and microfilaments play roles in trafficking of the
American Society for Microbiology.
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10. Infection of Vero Cells by BK Virus Is Dependent on Caveolae
Polyomavirus-associated nephropathy occurs in ∼5% of renal transplant recipients and results in loss of graft function in 50 to 70% of these patients. The disease is caused by reactivation of the common human polyomavirus BK (BKV) in the transplanted kidney. The early events in productive BKV infection are unknown. In this report, we focus on elucidating t
American Society for Microbiology.
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11. Differential cell-specific location of Cav-1 and Ca2+-ATPase in terminal Schwann cells and mechanoreceptive Ruffini endings in the periodontal ligament of the rat incisor
Caveolae are involved in clathrin-independent endocytosis, transcytosis, signal transduction, and tumor suppression – all of which depend on their main constituent protein caveolin families. The periodontal Ruffini ending has been reported to develop a caveola-like structure on the cell membrane of both the axon terminals and Schwann sheaths, suggesting th
Blackwell Science Inc.
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12. Human Papillomavirus Types 16, 31, and 58 Use Different Endocytosis Pathways To Enter Cells
The early steps of the intracellular trafficking of human papillomavirus type 16 (HPV-16), -31, and -58 pseudovirions were studied by investigating the effects of drugs acting at defined points of endocytosis pathways on virus-like particle-mediated pseudoinfection by overexpression of a dominant-negative form of the Eps15 protein to inhibit clathrin-mediate
American Society for Microbiology.