Cardiac Biomarkers
Mostrando 13-24 de 34 artigos, teses e dissertações.
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13. Exploring Vascular Function Biomarkers: Implications for Rehabilitation
Abstract The endothelium plays an important role in maintaining vascular homeostasis and regulating blood vessel function. Endothelial function is considered an independent predictor for risk of future cardiovascular events in cardiovascular and non-cardiovascular patients, as well as a predictor for postoperative complications in cardiovascular surgery pati
Braz. J. Cardiovasc. Surg.. Publicado em: 2017-04
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14. Salivary cortisol and α-amylase: subclinical indicators of stress as cardiometabolic risk
Currently, the potential for cardiovascular (CV) stress-induced risk is primarily based on the theoretical (obvious) side effects of stress on the CV system. Salivary cortisol and α-amylase, produced respectively by the hypothalamus-pituitary-adrenal (HPA) axis and the sympathetic-adrenomedullary (SAM) system during stress response, are still not included i
Braz J Med Biol Res. Publicado em: 06/02/2017
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15. Flax lignan concentrate attenuate hypertension and abnormal left ventricular contractility via modulation of endogenous biomarkers in two-kidney-one-clip (2K1C) hypertensive rats
ABSTRACT The present investigation was designed to study the effect of flax lignan concentrate obtained from Linum usitatissimum L., Linaceae, in two-kidney, one clip (2K1C) hypertension model in Wistar rats. 2K1C Goldblatt model rats were divided randomly into six groups: sham, 2K1C control, captopril (30 mg/kg), flax lignan concentrate (200, 400 and 800 mg
Rev. bras. farmacogn.. Publicado em: 2016-10
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16. Cardiac rehabilitation program in patients with Chagas heart failure: a single-arm pilot study
Abstract: INTRODUCTION: The benefit of a cardiac rehabilitation (CR) program for patients with Chagas heart failure (CHF) remains unclear. Therefore, we aimed to investigate the effects of CR for CHF patients. METHODS: A single-arm pilot study, including 12 patients with CHF, was performed. Patients participated in an 8-month physical exercise interventi
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-06
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17. Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease
Heart tissue inflammation, progressive fibrosis and electrocardiographic alterations occur in approximately 30% of patients infected by Trypanosoma cruzi, 10-30 years after infection. Further, plasma levels of tumour necrosis factor (TNF) and nitric oxide (NO) are associated with the degree of heart dysfunction in chronic chagasic cardiomyopathy (CCC). Thus,
Mem. Inst. Oswaldo Cruz. Publicado em: 2014-06
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18. Global microRNA profiles and signaling pathways in the development of cardiac hypertrophy
Hypertrophy is a major predictor of progressive heart disease and has an adverse prognosis. MicroRNAs (miRNAs) that accumulate during the course of cardiac hypertrophy may participate in the process. However, the nature of any interaction between a hypertrophy-specific signaling pathway and aberrant expression of miRNAs remains unclear. In this study, Spague
Braz J Med Biol Res. Publicado em: 11/04/2014
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19. Issues in solid-organ transplantation in children: translational research from bench to bedside
In this review, we identify important challenges facing physicians responsible for renal and cardiac transplantation in children based on a review of the contemporary medical literature. Regarding pediatric renal transplantation, we discuss the challenge of antibody-mediated rejection, focusing on both acute and chronic antibody-mediated rejection. We review
Clinics. Publicado em: 2014-01
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20. Comparing the diagnostic values of circulating microRNAs and cardiac troponin T in patients with acute myocardial infarction
OBJECTIVE: Recent studies have shown that circulating microRNAs might be useful, novel biomarkers for the diagnosis of acute myocardial infarction. The aims of this study were to evaluate the expression of cardiac-specific miRNAs (miR-1, -133a, -208b, and -499) in patients with acute myocardial infarction and to compare the diagnostic values of these miRNAs
Clinics. Publicado em: 2013-01
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21. Clinical implications of elevated serum soluble CD137 levels in patients with acute coronary syndrome
OBJECTIVES: Atherosclerosis is a chronic inflammatory disease. Research has focused on identifying specific serum biomarkers to detect vulnerable plaques. These markers serve as diagnostic tools for acute coronary syndrome and assist in identifying high-risk patients. However, the existing data are limited and conflicting. This study tested the hypothesis th
Clinics. Publicado em: 2013
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22. Identificação de alvos protéicos com potencial diagnóstico e prognóstico em doença arterial coronária / Identification of protein targets with potential diagnostic and prognostic in coronary artery disease
Worldwide, millions of patients are treated in emergencies because they had acute-onset chest pain, but only a portion is due to coronary syndrome. In situations like this is extremely important to distinguish when the chest pain is due to myocardial ischemia, as this is high risk and initiation of treatment should be immediate. New biomarkers are needed to
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2012
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23. Alterações hematológicas, hemostáticas e bioquímicas de cães tratados com anti-inflamatórios não esteroidais / Hematological, hemostatic and biochemical effects on nonsteroidal anti-inflammatory therapy in dogs
This study aimed to evaluate the heart and liver biomarkers, hematology and hemostasis in healthy dogs, submitted to therapy with nonsteroidal anti-inflammatory non-selective (NSAID), COX-2 preferential and COX-2 selective drugs. Were used 30 mongrel dogs, adults, males and females, clinically healthy, randomly divided into 5 groups (G) of 6 animals, that re
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/09/2011
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24. Hemostatic changes and clinical sequelae after on-pump compared with off-pump coronary artery bypass surgery: a prospective randomized study / Alterações hemostáticas e clínicas em cirurgias de revascularização miocárdica com e sem circulação extracorpórea: estudo prospectivo randomizado
Objective: To delineate the effects of extracorporeal bypass on biomarkers of hemostasis, fibrinolysis, and inflammation and clinical sequelae. Methods: Patients were assigned prospectively and randomly to either on-pump (n=41) or off-pump (n=51) coronary bypass surgery. The concentrations of C-reactive protein (CRP), fibrinogen, D-dimer, and plasminogen act
Publicado em: 2010