Cannabinoids Receptors
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. Perspectives in veterinary medicine on the use of cannabinoids as complementary palliative therapy for pain in cancer patients
RESUMO: A dor no paciente com câncer é uma manifestação clínica importante que resulta em baixa perspectiva de vida e pior prognóstico. Esta dor pode estar relacionada ao tipo de tumor, à invasão em tecidos adjacentes, metástases, procedimentos diagnósticos e terapêuticos, com resposta variável à terapêutica analgésica. Muitos estudos têm cha
Cienc. Rural. Publicado em: 28/02/2019
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2. Cirrhotic cardiomyopathy: the liver affects the heart
Cirrhotic cardiomyopathy historically has been confused as alcoholic cardiomyopathy. The key points for diagnosis of cirrhotic cardiomyopathy have been well explained, however this entity was neglected for a long time. Nowadays the diagnosis of this entity has become important because it is a factor that contributes significantly to morbidity-mortality in ci
Braz J Med Biol Res. Publicado em: 14/02/2019
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3. A spider derived peptide, PnPP-19, induces central antinociception mediated by opioid and cannabinoid systems
Abstract Background Some peptides purified from the venom of the spider Phoneutria nigriventer have been identified as potential sources of drugs for pain treatment. In this study, we characterized the antinociceptive effect of the peptide PnPP-19 on the central nervous system and investigated the possible involvement of opioid and cannabinoid systems in i
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 19/01/2017
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4. Cannabinoids, anxiety, and the periaqueductal gray
The use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties. As scientific research methods developed, the cannabinoids present in this herb were characterized, as well as their complex interface with the human central nervous system, provided by the activation of specific receptors.
Psychology & Neuroscience. Publicado em: 2010-06
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5. 1-(2,4-dichlorophenyl-1H-pyrazoles: Synthesis, Structural Analysis and Interactions with Cannabinoid Receptors CB1 / 1-(2,4-Diclorofenil)-1H-pirazóis: Síntese, Análise Estrutural e Interação com os Receptores Canabinóides CB1
A method to obtain fourteen enones [EtO2CC(O)C(R2)=C(R1)OR, where R = H, Me; R1 = Pr, Ph, 4-MeOC6H4, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-NO2C6H4, Fur- 2-yl; R2 = H; R1,R2 = -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)6-, 3,4-dihydronaphthalen-2-yl] from acylation of acetals with ethyl oxalyl chloride is reported. The cyclocondensation reaction of these substrat
Publicado em: 2010
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6. Estudo da modelagem molecular do receptor canabinóide CB1 e suas interações com o ∆9 - THC / Molecular modeling study of CB1 cannabinoid receptor and its interaction with delta-9-THC
Marijuana (Cannabis sativa) is a widely used plant and its various applications have important benefits. The plant Cannabis sativa has been used by man for centuries for eating, medicinal practices and religious rituals. In human subjects, its effects include analgesia, alterations in perceptions, cognition, memory and psychomotor activity. The cannabinoid c
Publicado em: 2009
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7. Sistema canabinóide e seu possível papel em processos de neuroproteção e plasticidade: estudos in vivo e in vitro. / The cannabinoid system and its possible role in neuroprotection and plasticity processes: in vivo and in vitro studies.
The cannabinoid system (CS) seems to have a role in several neurobiological processes, including neuroprotection and neuronal plasticity. The aims of this study were to verify the effects of unilateral retinal ablation on the expression of cannabinoid receptor CB1 and other structural proteins in the optic tectum of chick brain by immunohistochemistry, immun
Publicado em: 2008
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8. Aspectos terapêuticos de compostos da planta Cannabis sativa
Several cannabinoid compounds present therapeutic properties, but also have psychotropic effects, limiting their use as medicine. Nowadays, many important discoveries on the compounds extracted from the plant Cannabis sativa (cannabinoids) have contributed to understand the therapeutic properties of these compounds. The main discoveries in the last years on
Química Nova. Publicado em: 2006-04
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9. Endogenous cannabinoids induce fever through the activation of CB1 receptors
Blackwell Publishing Ltd.
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10. Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
The neuroprotective actions of cannabidiol and other cannabinoids were examined in rat cortical neuron cultures exposed to toxic levels of the excitatory neurotransmitter glutamate. Glutamate toxicity was reduced by both cannabidiol, a nonpsychoactive constituent of marijuana, and the psychotropic cannabinoid (−)Δ9-tetrahydrocannabinol (THC). Cannabinoids
National Academy of Sciences.
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11. The neurobiology and evolution of cannabinoid signalling.
The plant Cannabis sativa has been used by humans for thousands of years because of its psychoactivity. The major psychoactive ingredient of cannabis is Delta(9)-tetrahydrocannabinol, which exerts effects in the brain by binding to a G-protein-coupled receptor known as the CB1 cannabinoid receptor. The discovery of this receptor indicated that endogenous can
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12. Cannabinoid receptor localization in brain.
[3H]CP 55,940, a radiolabeled synthetic cannabinoid, which is 10-100 times more potent in vivo than delta 9-tetrahydrocannabinol, was used to characterize and localize a specific cannabinoid receptor in brain sections. The potencies of a series of natural and synthetic cannabinoids as competitors of [3H]CP 55,940 binding correlated closely with their relativ