Breast Cancer Risk
Mostrando 25-36 de 396 artigos, teses e dissertações.
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25. Hormone receptor-negative as a predictive factor for pathologic complete response to neoadjuvant therapy in breast cancer
RESUMO Objetivo Definir um fator preditivo para resposta patológica completa, comparar os resultados oncológicos associados com o grau de resposta patológica, após quimioterapia neoadjuvante, e analisar a resposta patológica completa como fator prognóstico para sobrevivência global e livre de progressão de doença. Métodos Estudo retrospectivo de
Einstein (São Paulo). Publicado em: 21/01/2019
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26. Survival rates of breast cancer and predictive factors: a hospital-based study from western Amazon area in Brazil
Resumo Na América Latina, a sobrevida de 5 anos do câncer de mama está abaixo dos países da Europa central. Não há estudos de sobrevida de câncer de mama de base hospitalar no oeste da Amazônia brasileira. O objetivo deste artigo é estimar a sobrevida hospitalar de câncer de mama e fatores associados em Rio Branco, Acre. Estudo de coorte de base ho
Ciênc. saúde coletiva. Publicado em: 2019-01
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27. Risk assessment of venous thromboembolism and thromboprophylaxis in pregnant women hospitalized with cancer: Preliminary results from a risk score
OBJECTIVES: Hospitalized patients with cancer are at high risk of developing venous thromboembolism, and the risk increases with pregnancy. The aim of this study was to apply a thromboprophylaxis protocol with a venous thromboembolism risk score for hospitalized pregnant women with cancer and to evaluate the effects on maternal morbidity and mortality. MET
Clinics. Publicado em: 18/10/2018
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28. Impact of a medication therapy management service offered to patients in treatment of breast cancer
ABSTRACT Cancer has high morbidity and mortality rates related to medication use and produce a costly impact in health care. Thus, patients require constant monitoring and proper coordination of care between different professionals. This study aimed to evaluate the impact generated by a Medication Therapy Management service (MTM) offered to patients with bre
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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29. Prevalence of dermatological complaints in patients undergoing treatment for breast cancer
Abstract: BACKGROUND: Internal malignancies such as breast cancer, as well as their treatment can often result in skin changes. OBJECTIVE: To assess the prevalence of dermatological complaints in patients who are undergoing oncological treatment for breast cancer in a hospital in Tubarão, Santa Catarina, Brazil. METHODS: Observational, cross-sectional st
An. Bras. Dermatol.. Publicado em: 2018-06
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30. Epidemiology Study on P53 (Rs1614984) C>T Mutation in Cigarette Smokers
ABSTRACT Epidemiology data have established that smoking is a prime threat for the cancers, largely lung cancer. Single-nucleotide polymorphisms (SNPs),P53 SNPs have been found to be associated with the predisposition of different cancers. Their decreased expression is reported in breast and lung cancer patients. p53 (rs1614984) had been reported to be linke
Braz. arch. biol. technol.. Publicado em: 18/05/2017
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31. Breast density pattern characterization by histogram features and texture descriptors
Abstract Introduction Breast cancer is the first leading cause of death for women in Brazil as well as in most countries in the world. Due to the relation between the breast density and the risk of breast cancer, in medical practice, the breast density classification is merely visual and dependent on professional experience, making this task very subjective
Res. Biomed. Eng.. Publicado em: 06/04/2017
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32. Breast cancer screening in developing countries
Developing countries have limited healthcare resources and use different strategies to diagnose breast cancer. Most of the population depends on the public healthcare system, which affects the diagnosis of the tumor. Thus, the indicators observed in developed countries cannot be directly compared with those observed in developing countries because the health
Clinics. Publicado em: 2017-04
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33. Neoadjuvant chemotherapy with trastuzumab in HER2-positive breast cancer: pathologic complete response rate, predictive and prognostic factors
The purpose of this study was to retrospectively review the pathologic complete response (pCR) rate from patients (n=86) with stage II and III HER2-positive breast cancer treated with neoadjuvant chemotherapy at our institution from 2008 to 2013 and to determine possible predictive and prognostic factors. Immunohistochemistry for hormone receptors and Ki-67
Braz J Med Biol Res. Publicado em: 26/01/2017
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34. Insulin-like Growth Factor 1 gene polymorphism and breast cancer risk
ABSTRACT Insulin-like Growth Factor-1 (IGF-1) gene polymorphism has been associated with an increased risk for breast cancer. IGF-1 is a key regulator of proliferation, cell differentiation and apoptosis. It has important mitogenic and anti-apoptotic activities in normal cells and in breast cancer cells, acting synergistically with estrogen to increase neopl
An. Acad. Bras. Ciênc.. Publicado em: 01/12/2016
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35. BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome
Abstract Approximately 5-10% of breast cancers are caused by germline mutations in high penetrance predisposition genes. Among these, BRCA1 and BRCA2, which are associated with the Hereditary Breast and Ovarian Cancer (HBOC) syndrome, are the most frequently affected genes. Recent studies confirm that gene rearrangements, especially in BRCA1, are responsible
Genet. Mol. Biol.. Publicado em: 2016-06
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36. Screening for germline BRCA1, BRCA2, TP53 and CHEK2 mutations in families at-risk for hereditary breast cancer identified in a population-based study from Southern Brazil
Abstract In Brazil, breast cancer is a public health care problem due to its high incidence and mortality rates. In this study, we investigated the prevalence of hereditary breast cancer syndromes (HBCS) in a population-based cohort in Brazils southernmost capital, Porto Alegre. All participants answered a questionnaire about family history (FH) of breast, o
Genet. Mol. Biol.. Publicado em: 24/05/2016