Beta Chemokine
Mostrando 1-12 de 57 artigos, teses e dissertações.
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1. Relationships Between Phenotype and Function of Blood CD4+ T-Cells and Ascending Thoracic Aortic Aneurysm: an Experimental Study
Abstract Introduction: Non-familial ascending thoracic aorta dilation and aneurysms (TAAs) are silent diseases in elderly patients. Histopathology revealed that functionally polarized infiltrating CD4+ T-cells play a key role in aortic wall weakening. Objective: To evaluate the possible associations between phenotype and cytokine production of circulating
Braz. J. Cardiovasc. Surg.. Publicado em: 2019-02
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2. Evaluation of short-interfering RNAs treatment in experimental rabies due to wild-type virus
ABSTRACTWe have evaluated the efficacy of short-interfering RNAs targeting the nucleoprotein gene and also the brain immune response in treated and non-treated infected mice. Mice were inoculated with wild-type virus, classified as dog (hv2) or vampire bat (hv3) variants and both groups were treated or leaved as controls. No difference was observed in the le
Braz J Infect Dis. Publicado em: 2015-10
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3. Efeito da Quimiocina CXCL10 na infecÃÃo por Leishmania infantum/chagasi em camundongos BALB/C / Effect of chemokine CXCL10 in Leishmania infantum chagasi infection in BALB/c mice.
A leishmaniose visceral causada por Leishmania infantum chagasi à caracterizada pela perda da habilidade do hospedeiro gerar uma resposta imunolÃgica eficaz. Neste estudo, foi investigado o papel da quimiocina CXCL10 no controle da infecÃÃo por L. infantum chagasi in vivo. Grupos de camundongos BALB/c foram tratados ou nÃo com CXCL10 (5 μg/kg) com
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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4. Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni
The recruitment of circulating eosinophils by chemokines and chemokine receptors plays an important role in the inflammation process in acute human schistosomiasis. Our main focus has been on the plasma chemokines (CXCL8/CCL2/CCL3/CCL24) and chemokine receptors (CCR2/CCR3/CCR5/CXCR1/CXCR2/CXCR3/CXCR4) expressed by circulating eosinophils from acute Schistoso
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-07
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5. Peptídeos urinários no transplante renal humano: busca de um perfil diferencial na tolerância operacional / Urine peptides in human kidney transplantation: research for a differential profile on operational tolerance
Um grupo especial de indivíduos transplantados renais mantém a função do enxerto estável após a total retirada da terapia imunossupressora, alcançando um estado imunológico chamado de Tolerância operacional. Ainda não há marcadores moleculares e celulares que discriminem a tolerância no transplante humano, e os seus mecanismos estão sendo invest
Publicado em: 2010
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6. High expression of co-stimulatory and adhesion molecules are observed on eosinophils during human Schistosoma mansoni infection
Herein we have focused attention on major phenotypic features of peripheral blood eosinophils from chronic Schistosoma mansoni-infected patients. For this purpose, detailed immunophenotypic profiles of a range of cell surface markers were performed, including activation markers (CD23/CD69/CD25/HLA-DR), co-stimulatory molecules (CD28/CD80/CD86), chemokine rec
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-10
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7. The beta-chemokines MIP-1alpha and RANTES and lipoprotein metabolism in HIV-infected brazilian patients
HIV patients are predisposed to the development of hypertriglyceridemia and hypercholesterolemia as a result of both viral infection and HIV infection therapy, especially the protease inhibitors. Chemokines and cytokines are present at sites of inflammation and can influence the nature of the inflammatory response in atherosclerosis. We investigated the corr
Brazilian Journal of Infectious Diseases. Publicado em: 2005-08
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8. Study of the CCR5-m303 mutation in three different ethnic groups from Brazil
The main coreceptor gene involved in HIV-1 infection is CCR5 beta chemokine receptor gene for which several mutations have been described, some of which have correlated with HIV-1 infection, acquired immune deficiency syndrome (AIDS), or both. Deletion of 32bp in the CCR5 gene (delta32) has been shown to confer resistance to infection by HIV-1 R5 strains. An
Genetics and Molecular Biology. Publicado em: 2005
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9. CCR5D32 mutation in three Brazilian populations of predominantly Sub-Saharan African ancestry
This study reports the frequencies of the CCR5D32 mutation of the beta-chemokine 5 gene and discusses the possible effects of past and recent gene flow in three quilombo remnants (Brazilians communities with anthropological African ancestry whose ancestors were escaped slaves): Rio das Rãs, Mocambo, and São Gonçalo in the northeastern region of Brazil. Th
Genetics and Molecular Biology. Publicado em: 2004
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10. Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population
Entry of human immunodeficiency type 1 virus (HIV-1) into target cells requires both CD4and one of the chemokine receptors. Viruses predominantly use one, or occasionally both, of the major co-receptors CCR5 and CXCR4, although other receptors, including CCR2B and CCR3, function as minor co-receptors. A 32-nucleotide deletion (delta32) within the beta-chemok
Brazilian Journal of Infectious Diseases. Publicado em: 2003-08
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11. High Beta-Chemokine Expression Levels in Lymphoid Tissues of Simian/Human Immunodeficiency Virus 89.6-Vaccinated Rhesus Macaques Are Associated with Uncontrolled Replication of Simian Immunodeficiency Virus Challenge Inoculum
Viral suppression by noncytolytic CD8+ T cells, in addition to that by classic antiviral CD8+ cytotoxic T lymphocytes, has been described for human immunodeficiency virus and simian immunodeficiency virus (SIV) infections. However, the role of soluble effector molecules, especially beta-chemokines, in antiviral immunity is still controversial. In an attenuat
American Society for Microbiology.
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12. Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.
Two chemokine (chemoattractant cytokines) beta peptides, macrophage inflammatory proteins 1 alpha and 1 beta (MIP-1 alpha and MIP-1 beta), were induced in human monocyte cultures following infection with the human immunodeficiency virus type 1 (HIV-1). Induction depended on productive viral infection: not only did the kinetics of MIP-1 peptide induction clos