Benzodiazepine
Mostrando 13-24 de 197 artigos, teses e dissertações.
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13. Monoterpenoids (thymol, carvacrol and S-(+)-linalool) with anesthetic activity in silver catfish (Rhamdia quelen): evaluation of acetylcholinesterase and GABAergic activity
This study evaluated the anesthetic potential of thymol and carvacrol, and their influence on acetylcholinesterase (AChE) activity in the muscle and brain of silver catfish (Rhamdia quelen). The AChE activity of S-(+)-linalool was also evaluated. We subsequently assessed the effects of thymol and S-(+)-linalool on the GABAergic system. Fish were exposed to t
Braz J Med Biol Res. Publicado em: 19/10/2017
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14. Patterns of chronic benzodiazepine use in the elderly
Abstract Background In several countries, prevalence studies demonstrate that chronic use of BZD in the elderly population is very high. This scenario has reached pandemic proportions for decades and is an important public health problem. Objectives To examine the independent association between chronic benzodiazepine use in depression, anxiety and bipol
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2016-08
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15. Avaliação da dependência e da ansiedade em usuários de benzodiazepínicos em um município do interior do Rio Grande do Sul
Resumo Introdução: Os benzodiazepínicos estão entre os medicamentos mais prescritos para ansiedade, e entre as classes farmacológicas mais utilizadas no mundo, apresentando alto potencial de dependência. O objetivo deste estudo foi verificar o nível de dependência e ansiedade entre os usuários desses medicamentos no sistema público de saúde. M�
Trends Psychiatry Psychother.. Publicado em: 27/06/2016
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16. Involvement of GABAergic pathway in the sedative activity of apigenin, the main flavonoid from Passiflora quadrangularis pericarp
Abstract In the current study we showed that oral administration of an aqueous extract of Passiflora quadrangularis L., Passifloraceae, pericarp results in a significant prolongation of the sleep duration in mice evaluated in the ethyl ether-induced hypnosis test which indicates sedative effects. Apigenin, the main flavonoid of the extract, induced a similar
Rev. bras. farmacogn.. Publicado em: 2015-04
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17. Temperament and character traits associated with the use of alcohol, cannabis, cocaine, benzodiazepines, and hallucinogens: evidence from a large Brazilian web survey
Objectives: To evaluate how personality traits are associated with occasional use, abuse, and dependence of alcohol, cannabis, cocaine, benzodiazepines, and hallucinogens in a large availability sample of adults via online questionnaires. Methods: The sample consisted of 8,646 individuals (24.7% men and 75.3% women) who completed an anonymous web survey. In
Rev. Bras. Psiquiatr.. Publicado em: 20/01/2015
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18. Sexual dysfunction and dissatisfaction in chronic hepatitis C patients
IntroductionThe prevalence of sexual dysfunction (SD) and dissatisfaction with sexual life (DSL) in patients with chronic hepatitis C virus infection (CHC) was jointly investigated via a thorough psychopathological analysis, which included dimensions such as fatigue, impulsiveness, psychiatric comorbidity, health-related quality of life (HRQL) and sociodemog
Rev. Soc. Bras. Med. Trop.. Publicado em: 2014-10
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19. Evaluation of cytotoxicity and mutagenicity of the benzodiazepine flunitrazepam in vitro and in vivo
Flunitrazepam (FNZ) é um sedativo benzodiazepínico prescrito para o tratamento da insônia em curto prazo. Entretanto, existe a preocupação com relação aos possíveis efeitos carcinogênicos ou genotóxicos causados por este fármaco. Então, o objetivo deste estudo foi avaliar os efeitos citotóxicos, clastogênicos e aneugênicos do FNZ em células d
Braz. J. Pharm. Sci.. Publicado em: 2014-04
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20. Sedative and anesthetic activities of the essential oils of Hyptis mutabilis (Rich.) Briq. and their isolated components in silver catfish (Rhamdia quelen)
This study evaluated the sedative and anesthetic effects of the essential oils (EO) of Hyptis mutabilis (Rich.) Briq. and their isolated components on silver catfish (Rhamdia quelen). Quantitative chemical differences between the EOs obtained from leaves and inflorescences were verified, and a new chemotype rich in globulol was described. Although there were
Braz J Med Biol Res. Publicado em: 18/09/2013
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21. Impairment of locomotor activity induced by the novelN-acylhydrazone derivatives LASSBio-785 and LASSBio-786 in mice
The N-acylhydrazone (NAH) analogues N-methyl 2-thienylidene 3,4-benzoylhydrazine (LASSBio-785) and N-benzyl 2-thienylidene 3,4-benzoylhydrazine (LASSBio-786) were prepared from 2-thienylidene 3,4-methylenedioxybenzoylhydrazine (LASSBio-294). The ability of LASSBio-785 and LASSBio-786 to decrease central nervous system activity was investigated in male Swiss
Braz J Med Biol Res. Publicado em: 19/03/2013
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22. Estudo da atividade tipo-ansiolítica das folhas de Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae / Anxiolity - like activity of the leaves of Pimenta pseudocaryophyllus (Gomes) L.R. Landrum - Myrtaceae
Pimenta pseudocaryophyllus, popularly known as Craveiro, is the only species in this genus native to the cerrado of Brazil. Ethnopharmacological studies revealed medicinal use of P. pseudocaryophyllus extracts in treating menstrual and digestive problems as well as emotional tension in the form of soothing tea among other therapeutic applications in Brazilia
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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23. Avaliação dos efeitos da cetamina racêmica, cetamina s (+) e midazolam em jibóias boa constrictor linnaeus, 1758 (squamata: boidae)
CAPÍTULO 2: Visto o crescimento na criação de serpentes como animais de estimação, além de sua utilização em escala comercial, a contenção farmacológica utilizada durante procedimentos clínicos e cirúrgicos tornou-se indispensável. Assim, objetivou-se comparar os efeitos da cetamina racêmica e cetamina S (+) em Boa constrictor. Utilizaram-se 2
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/11/2011
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24. Influência do ciclo estral no efeito do diazepam na ansiedade e memória de ratas
Memory and anxiety are related phenomena. Several evidences suggest that anxiety is fundamental for learnining and may facilitate or impair the memory formation process depending of the context. The majority of animal studies of anxiety and fear use only males as experimental subjects, while studies with females are rare in the literature. However, the preva
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/05/2011