Basal Cell Nevus Syndrome
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Novel mutation in PTCH1 gene in a patient with basal cell nevus syndrome and uterus bicornis
An. Bras. Dermatol.. Publicado em: 17/10/2019
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2. Solitary plantar basal cell carcinoma
Abstract: Basal cell carcinoma is the most frequent skin cancer, generally located in hair-bearing, sunlight-exposed areas. Basal cell carcinoma usually occurs on the head and neck, but very rarely on extra-facial locations. We report a case of a 65-year-old woman presenting with a solitary non-healing ulcer on the sole of the right foot for two years. Histo
An. Bras. Dermatol.. Publicado em: 2018-06
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3. Clinical and PTCH1 gene mutations studies in patients bearing multiple familiar non-syndromic basal cell carcinomas / Estudo clínico e de mutações no gene PTCH1 em pacientes portadores de carcinomas basocelulares múltiplos familiares não sindrômicos
INTRODUCTION: Basal cell carcinomas (BCC) are the most usual skin cancer that affects human beings. Sporadic BCCs are prevalent, often arising in people chronically exposed to UV radiation from the sun. Eventually BCCs may be associated to different syndroms like Bazex-Dupré-Christol, Rambo and Gorlin. Contrarily to syndromic BCCs, the cases of multiple fam
Publicado em: 2010
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4. Treatment of cutaneous tumors with topical 5% imiquimod cream
INTRODUCTION: There are various approaches to the treatment of cutaneous tumors; one of them is treatment with imiquimod, a synthetic toll-like receptor agonist with a low molecular weight that offers a topical, noninvasive, and non-surgical therapeutic option. The main objective of our study was to provide data on 89 patients who used a 5% imiquimod cream f
Clinics. Publicado em: 2009
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5. Medical genetics: advances in brief: Human homolog of patched, a candidate gene for the basal cell nevus syndrome
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6. Characterization of two patched receptors for the vertebrate hedgehog protein family
The multitransmembrane protein Patched (PTCH) is the receptor for Sonic Hedgehog (Shh), a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. Current models suggest that binding of Shh to PTCH prevents the normal inhibition of the seven-transmembrane-protein Smoothened (SMO) by PTCH. According to this model, the inhibi
The National Academy of Sciences.