Astrocytoma
Mostrando 1-12 de 155 artigos, teses e dissertações.
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1. DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance
Abstract Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. On average, patients survive 14.6 months after diagnosis and less than 5% survive five years or more. Several pieces of evidence have suggested that the DNA damage signaling and repair activities are directly correl
Genet. Mol. Biol.. Publicado em: 13/12/2019
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2. Expression of estrogen and progesterone receptors in astrocytomas: a literature review
Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones. A literature review for the presence of estrogen and progesterone receptors in astrocytomas was conducted in the PubMed database using the following MeSH terms: “estrogen
Clinics. Publicado em: 2016-08
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3. Phytochemical study and evaluation of cytotoxic and genotoxic properties of extracts from Clusia latipes leaves
Abstract Some species of the Clusia genus have been shown to have important biomedical properties, including the ability to inhibit tumor growth in vitro and the usefulness for skin care. In this study, we examined the cytotoxic effect of hexane, ethyl acetate and methanol extracts from Clusia latipes Planch. & Triana, Clusiaceae, leaves on survival of human
Rev. bras. farmacogn.. Publicado em: 2016-02
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4. Pilocytic astrocytoma and pleomorphic xanthoastrocytoma: glioneuronal tumors or variants of ganglioglioma?
J. Bras. Patol. Med. Lab.. Publicado em: 2013-06
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5. A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi
Astrocytes play a vital role in neuronal protection, homeostasis, vascular interchange and the local immune response. Some viruses and parasites can cross the blood-brain barrier and infect glia. Trypanosoma cruzi, the aetiological agent of Chagas disease, can seriously compromise the central nervous system, mainly in immune-suppressed individuals, but also
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-04
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6. Intellectual aspects of cognitive performance in children after treatment for medulloblastoma and astrocytoma
The present study investigated the relationship between posterior fossa tumors (astrocytoma and medulloblastoma) and their respective treatments and cognitive performance in Brazilian children by measuring Intelligence Quotient (IQ). Twenty children were enrolled in the study, of whom 13 were diagnosed with astrocytoma (average age at evaluation, 10.2 years;
Psychology & Neuroscience. Publicado em: 2010-12
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7. Xenograft transplantation of human malignant astrocytoma cells into immunodeficient rats: an experimental model of glioblastoma
INTRODUCTION: Astrocytic gliomas are the most common intracranial central nervous system neoplasias, accounting for about 60% of all primary central nervous system tumors. Despite advances in the treatment of gliomas, no effective therapeutic approach is yet available; hence, the search for a more realistic model to generate more effective therapies is essen
Clinics. Publicado em: 2010
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8. Alterações metabólicas e o papel da mitocôndria no processo de tumorigênese de astrocitomas humanos / Metabolic alterations and the role of mitochondria in tumorigenic process of human astrocytomas
Mitochondria has a key role in cell survival and death. Mitochondrial DNA (mtDNA) alterations, for example, amplification, homoplasmic mutation, deletion and depletion, and their clinical and pathological implications have been analyzed in human malignancies. In order to search for mitochondrial alterations associated to tumorigenesis, this study aimed to an
Publicado em: 2010
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9. Neoplasias intracranianas em cães: avaliação imuno-histoquímica de marcadores de proliferação celular e expressão de p53 / Intracranial neoplasia in dogs: immunohistochemistry evaluation of cellular proliferation markers and p53 expression
O estudo das alterações neoplásicas do sistema nervoso (SN) de cães apresenta enorme desafio devido suas particularidades, entre as espécies de animais domésticos o cão Canis familiares é o que apresenta a maior ocorrência destes neoplasmas. O desenvolvimento deste trabalho visa estabelecer o estudo anátomopatológico, molecular e epidemiológico e
Publicado em: 2009
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10. Analise de possiveis mecanismos e consequencias funcionais da expressão de galectina-3 em celulas de glioma expostas a condições hipoxicas / Analysis of possible mechanisms and functional consequences of galectin-3 expression in glioma cells exposed to hypoxia
Gliomas are primary Central Nervous System tumors. Among them, glioblastomas are the most common clinical forms and have the worst prognosis. In an attempt to understand glioma biology, the NG97 cell line was established. This cell line presents glioblastoma s characteristics, showing nuclear atipia and high growth rate. Recently, it was discovered that this
Publicado em: 2009
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11. Polymorphisms of EGF e EGFR genes in diffusely infiltrative astrocytomas / Estudo de polimorfismos dos genes EGF e EGFR em astrocitomas difusamente infiltrativos
INTRODUÇÃO: Os astrocitomas difusamente infiltrativos são os tumores mais freqüentes de Sistema Nervoso Central (SNC) com uma taxa de 5-7 novos casos por 100.000 pessoas ano. São tumores altamente invasivos e estão associados com alterações de alguns genes como EGF (fator de crescimento epidérmico) e o EGFR (receptor do fator de crescimento epidérm
Publicado em: 2008
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12. Analysis of P2X2 e P2X4 receptors during neuronal differentiation / Análise dos receptores P2X2 e P2X4 durante a diferenciação neuronal
During the development of the nervous system, oscillations of intracellular calcium concentrations activate programs of gene expression resulting in proliferation, migration and neuronal differentiation of embryonic cells. In this thesis, the participation of ionotropic P2X2 and P2X4 receptor subtypes, whose receptor channels are highly permeable for calcium
Publicado em: 2007