Utilização de proteinas derivadas da matriz do esmalte (EMDOGAIN) no tratamento de defeitos intra-osseos : estudo longitudinal clinico e radiografico

AUTOR(ES)
DATA DE PUBLICAÇÃO

2003

RESUMO

The aim of the present study was to compare the clinical and radiographical effects of the treatment of intrabony periodontal defects with or without the use of a gel composed of enamel matrix proteins derivative (EMDOGAIN TRADEMARK ). Fifteen patients, exhibiting a total of 19 defects 1 and 2 wall intrabony defects on one-rooted teeth, were randomly divided into test and control groups. Prior to surgery (baseline), 6 and 18 months after it the following parameters were evaluated using oclusal stents: relative gingival recession (RGR), relative clinical attachment levei (RCAL) and probing depth (PD). Linear radiographic measurements were obtained at the same time during this period through standard digital radiographies. Data were statistically analyzed using ANOVA and Tukey s Studentized Range Test (p<0,05). The clinical results demonstrated that after 18 months there was a reduction in probing depth of 3.2 : + or - 1.44mm and a gain in the clinical attachment levei of 1.4 + or - 1.26mm on average for the test group. As for the control group the reduction in the probing depth was of 2.7 + or - 0.89mm and the gain in the clinical attachment levei was of 1.2 + or - 0.78mm on average. Radiographically, there was an average bone filling of 1.64 + or - 1.69mm in the test group and 0.7 + or - 1.9mm in the control group. The two treatments improved clinical parameters as compared to baseline, but the differences found between the groups were not statistically significant. Therefore, it may be concluded that both therapies have similar effects in promoting probing depth reduction, clinical attachment gain, and defect bone till in the 18th month post treatment. A study involving a larger sample size is necessary to statistically confirm the equivalence between the two treatment modalities

ASSUNTO(S)

enamel matrix proteins intrabony periodontal defects doença periodontal periodontia cirurgia linear radiographic measurements periodontal therapy

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