USO DA BIOIMPEDÂNCIA NO ACOMPANHAMENTO DE PACIENTES EM QUIMIOTERAPIA: ALTERAÇÕES NO ÂNGULO DE FASE

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

Background &Aims: Phase angle (PA), determined by bioelectrical impedance analysis (BIA), has been considered as a prognostic factor in several clinical conditions. The objective of this study is to investigate PA as a prognostic factor for survival in cancer patients. Methods: A prospective study was conducted in 195 patients, in the beginning of chemotherapy. BIA was performed in all patients and standardized PA (SPA) was calculated. The Kaplan-Meier method was used to calculated survival. Cox regression method was used to evaluate the independent prognostic effect of phase angle, after adjustment for other variables. Results: Patients with SPA - 2 s.d. had a significant smaller median survival when we compared to those with SPA >- 2 s.d. (p <0.001). Using Cox regression, the mortality rate was higher in patients with SPA - 2 s.d. (RR 3.24 CI: 2.10 4.98; p <0.001). After adjustment for age, sex, marital status, social class, type of chemotherapy, tumor localization and stage, patients with PA - 2 s.d. still have a higher mortality rate (RR 2.17 CI: 1.35 3.5; p = 0.001). Conclusions: The present study demonstrates that phase angle is an independent prognostic indicator in cancer patients

ASSUNTO(S)

ângulo de fase cancer survival bioimpedância elétrica fatores prognósticos phase angle medicina câncer sobrevida bioelectrical impedance analysis prognostic indicator

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