The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients
AUTOR(ES)
Fonseca, Renata Fragelli, Kawamura, Marcia Tie, Oliveira, José Antônio, Teixeira, Anselmo, Alves, Gilda, Carvalho, Maria da Glória da Costa
FONTE
Mem. Inst. Oswaldo Cruz
DATA DE PUBLICAÇÃO
2012-11
RESUMO
Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.
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