The outer membranes of Brucella spp. are not barriers to hydrophobic permeants.

AUTOR(ES)

Martínez de Tejada, G

RESUMO

The patterns of susceptibility to hydrophobic and hydrophilic drugs and the uptake of the fluorescent probe N-phenyl-naphthylamine in Brucella spp., Haemophilus influenzae, Escherichia coli, and deep rough Salmonella minnesota mutants were compared. The results show that the outer membranes of smooth and naturally rough Brucella spp. do not represent barriers to hydrophobic permeants and that this absence of a barrier relates at least in part to the properties of Brucella lipopolysaccharide.

Documentos Relacionados

• The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides.
• The Outer Membrane of Brucella ovis Shows Increased Permeability to Hydrophobic Probes and Is More Susceptible to Cationic Peptides than Are the Outer Membranes of Mutant Rough Brucella abortus Strains
• Outer Membrane Proteins Omp10, Omp16, and Omp19 of Brucella spp. Are Lipoproteins
• Characterization of New Members of the Group 3 Outer Membrane Protein Family of Brucella spp.
• Limited Genetic Diversity of Brucella spp.