Sequencing DNA using mass spectrometry for ladder detection.
AUTOR(ES)
Taranenko, N I
RESUMO
Sequencing of DNA fragments of 130 and 200 bp using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for DNA ladder detection was demonstrated. With further improvement in mass resolution and detection sensitivity, mass spectrometry shows great promise for routine DNA sequencing in the future.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=147544Documentos Relacionados
- DNA sequencing using biotinylated dideoxynucleotides and mass spectrometry
- Specific-primer-directed DNA sequencing using automated fluorescence detection.
- Method for phosphorothioate antisense DNA sequencing by capillary electrophoresis with UV detection.
- RNA sequencing using fluorescent-labeled dideoxynucleotides and automated fluorescence detection.
- A procedure for selective DNA alkylation and detection by mass spectrometry.