Relationships between cotransducible plasmids in Staphylococcus aureus.
AUTOR(ES)
Iordănescu, S
RESUMO
Cotransduction of two or even three plasmids was observed when a Staphylococcus aureus strain, carrying five distinct, compatible plasmids, was used as donor. An active host recombination system did not seem to be indispensable for plasmid cotransduction, since RecA+ and RecA- donors gave similar cotransduction frequencies. Analysis of plasmids carried by cotransductant clones demonstrated that a genetic interaction can take place between cotransduced plasmids, leading to new plasmids. Some of the properties of these new plasmids are discussed. Another set of experiments tested the ability of a cotransducible plasmid to allow a significant degree of multiplication of a temperature-sensitive plasmid at restrictive temperature. In an attempt to explain the results obtained, a working hypothesis suggesting a transient and reversible association of cotransducible plasmids is presented.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=234896Documentos Relacionados
- Relationships Between Cotransducible Plasmids in Staphylococcus aureus
- Site-specific recombination between plasmids of Staphylococcus aureus.
- Molecular relationships among serogroup B bacteriophages of Staphylococcus aureus.
- Comparative analysis of conjugative plasmids mediating gentamicin resistance in Staphylococcus aureus.
- Analysis of plasmids in nosocomial strains of multiple-antibiotic-resistant Staphylococcus aureus.