phs Locus of Escherichia coli, a mutation causing pleiotropic lesions in metabolism, is an rpoA allele.

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RESUMO

The phs mutation, which causes a pleiotropic growth defect, has been mapped and shown to be an allele of rpoA, the gene for the alpha subunit of RNA polymerase. The mutation is shown to cause a transcription defect in the arabinose operon, araBAD.

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