NMR study of 1,4-dihydropyridine derivatives endowed with long alkyl and functionalized chains
AUTOR(ES)
Suárez, Margarita, Molero, Dolores, Salfrán, Esperanza, Rodríguez, Hortensia, Coro, Julieta, Sáez, Elena, Martínez-Álvarez, Roberto, Martín, Nazario
FONTE
Journal of the Brazilian Chemical Society
DATA DE PUBLICAÇÃO
2011-01
RESUMO
Neste trabalho, realizou-se um estudo por ressonância magnética nuclear de ¹H, 13C e 15N de derivados de 1,4-dihidropiridinas que contêm, nos grupos ésteres das posições C-3 e C-5, longas cadeias alquílicas ou funcionalizadas. Atribuíram-se inequivocamente os sinais dos espectros utilizando experimentos 1D e 2D (DEPT, nOe, HMQC, HMBC, COSY).
Documentos Relacionados
- Unexpected diastereotopic behaviour in the ¹H NMR spectrum of 1,4-dihydropyridine derivatives triggered by chiral and prochiral centres
- High-affinity antibodies to the 1,4-dihydropyridine Ca2+-channel blockers.
- Subunit composition of skeletal muscle transverse tubule calcium channels evaluated with the 1,4-dihydropyridine photoaffinity probe, [3H]azidopine.
- Purified skeletal muscle 1,4-dihydropyridine receptor forms phosphorylation-dependent oligomeric calcium channels in planar bilayers.
- Identification of 1,4-dihydropyridine binding regions within the alpha 1 subunit of skeletal muscle Ca2+ channels by photoaffinity labeling with diazipine.
