Microwave-assisted clean synthesis of amides via aza-wittig reaction under solvent-free condition

AUTOR(ES)

Sathishkumar, Murugan, Nagarajan, Sangaraiah, Velan, Poovan Shanmuga, Dinesh, Murugan, Ponnuswamy, Alagusundaram

FONTE

Journal of the Brazilian Chemical Society

DATA DE PUBLICAÇÃO

2011-11

RESUMO

O acoplamento de fosfazenos com cloretos de acila ou anidridos carboxílicos mediado por microondas na presença de fosfito de etila foi realizado, resultando nas correspondentes amidas, de maneira limpa e com bons rendimentos. Ao contrário das metodologias anteriores, que empregam solventes clorados, benzeno (cancerígeno), etc, este protocolo é eco-amigável, rápido e simples.

Documentos Relacionados

• Microwave-assisted Passerini reactions under solvent-free conditions
• Microwave-assisted synthesis under solvent-free conditions of (E)-2-(Benzo[d]thiazol-2-yl)-3-arylacrylonitriles
• Efficient synthesis of sulfonamide derivatives on solid supports catalyzed using solvent-free and microwave-assisted methods
• Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures
• Pyrazole synthesis under microwave irradiation and solvent-free conditions