Lepromatous leprosy, melanoma, and basal cell carcinoma: clinical-histopathologic association

AUTOR(ES)

Braghiroli, Cintia Santos

FONTE

An. Bras. Dermatol.

DATA DE PUBLICAÇÃO

09/12/2019

RESUMO

Abstract Cutaneous neoplasms frequently occur in leprosy, but there are few reports of the coexistence of leprosy and basal cell carcinoma in the same lesion. This case reports a 49-year-old male with an ulcerated plaque on the right lateral nasal wall, bright papules on the sternal region, and a blackened plaque on the right temporal region. The nasal and temporal lesions were diagnosed by histopathology as basal cell carcinoma and melanoma, respectively. The sternal lesions were excised with the repair of the “dog ear” which histopathological examination showed macrophages in the dermis parasitized with acid-fast bacilli, confirming the diagnosis of lepromatous leprosy with Fite-Faraco staining. This case report highlights the importance of referring the dog-ear specimen for histopathologic analysis.

Documentos Relacionados

• Basal cell carcinoma of the skin with areas of squamous cell carcinoma: a basosquamous cell carcinoma?
• Dermatoscopy in polypoid basal-cell carcinoma: a rare histopathological variation
• DNA repair and aging in basal cell carcinoma: a molecular epidemiology study.
• Lymphocyte transformation test in leprosy: decreased lymphocyte reactivity to Mycobacterium leprae in lepromatous leprosy, with no evidence for a generalized impairment.
• Apoptotic and mitotic indices in malignant melanoma and basal cell carcinoma.