In Vivo-Induced Genes in Pseudomonas aeruginosa

AUTOR(ES)

Handfield, Martin

FONTE

American Society for Microbiology

RESUMO

In vivo expression technology was used for testing Pseudomonas aeruginosa in the rat lung model of chronic infection and in a mouse model of systemic infection. Three of the eight ivi proteins found showed sequence identity to known virulence factors involved in iron acquisition via an open reading frame (called pvdI) implicated in pyoverdine biosynthesis, membrane biogenesis (FtsY), and adhesion (Hag2).

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