Gastroesphageal reflux disease : influence of cagA strains of Helicobacter pylori in the proton pump inhibition therapeutic response in patients with low grade erosive esophagitis / "Doença do refluxo gastroesofágico: influência da cepa cagA do Helicobacter pylori na resposta terapêutica à inibição da bomba protônica em pacientes com esofagite erosiva leve"

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

Eighty three patients with grade I-II of the modified Savary-Miller classification have been studied. They were divided in three groups. One without Helicobacter pylori infection, two with the bacterium, one with and other without the cagA gene. We verified the influence of cagA status, histopathology of antrum and body of the stomach and gastrinemia in the esophageal healing rates after treatment with pantoprazole 40 mg once a day for six weeks. Helicobacter pylori presence but not cagA status and gastrinemia led to better healing rates. Histopathology of the gastric mucosa did not influence the response

ASSUNTO(S)

esophagitis peptic/therapy esofagite péptica/terapia helicobacter pylori/drug effects helicobacter pylori/efeitos de drogas benzimidazóis benzimidazoles

ACESSO AO ARTIGO

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