Fatores associados á infecção por Toxoplasma gondii em gestantes atendidas nas unidades básicas de saúde do município de Rolândia, Paraná

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

The aim of this study was to determine the prevalence against IgG and IgM anti-Toxoplasma gondii antibodies in pregnant women attended in Health Basic Unities (UBS) in Rolândia city -Paraná-Brasil, and identify factors associated with infection by T. gondii. The prenatal screening program was implemented in the city in July 2007. 320 pregnant women were evaluated until February 2008, Group I (G I) by Immunofluorescence Assay (IFA) to detect IgG anti-T. gondii and Microparticle Enzyme Immunoassay (MEIA), Abbott  for IgM. From March to October 2008 were evaluated 273 pregnat, Group II (G II), with Enzyme-linked Immunosorbent Assay (ELISA) to detect IgG and capture ELISA for IgM, both from  DiaSorin. All samples IgG and IgM reactive were evaluated by IgG Avidity test, LIAISON . From the 320 pregnats, from the G I, 170 (53.1%) were reagent for IgG and nonreagent for IgM; 6 (1.9%) were reagent for IgG and IgM; one (0.3%) was nonreagent for IgG and reagent for IgM and 144 (45.0%) were nonreagent for IgG and IgM. All the IgG and IgM reagent serum, were from women who were in the first trimester of pregnancy and tested using the IgG-Avidity, showing strong results. At G II, from the 273 pregnant women analyzed, 151 (55.3%) were reagent for IgG and nonreagent for IgM and 122 (44.7%) were nonreagent for IgG and IgM. It was considered an overall prevalence of 55.1% of reagent IgG on both groups and through statistical analysis it was discovered that there was no difference in prevalence between the groups. The variables associated (p ≤ 0.05) to the presence of IgG were: residence in rural areas, women aged between 35 and 45 years, low educational level (≤ 8 years of study), monthly family income less than 1 minimum wage, more than one pregnancy, drinking water from a non-public water supply, habit of handling soil or sand and tendency (p=0,0524) in the habit of handling raw meat. Guidelines for primary prevention measures and trimester serological monitoring of seronegative pregnant women (risk group) are important measures for preventing congenital toxoplasmosis.

ASSUNTO(S)

doenças parasitárias em gestantes toxoplasmose - prevenção toxoplasmose - diagnóstico toxopasma gondii doenças congênitas parasitic diseases in pregnant women toxoplasmosis prevention

ACESSO AO ARTIGO

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