Evidence for the co-circulation of dengue virus type 3 genotypes III and V in the Northern region of Brazil during the 2002-2004 epidemics

AUTOR(ES)

Nogueira, Meri Bordignon, Stella, Vanessa, Bordignon, Juliano, Batista, Weber Cheli, Borba, Luana de, Silva, Luis Hildebrando Pereira da, Hoffmann, Federico Guillermo, Probst, Christian Macagnan, Santos, Claudia Nunes Duarte dos

FONTE

Memórias do Instituto Oswaldo Cruz

DATA DE PUBLICAÇÃO

2008-08

RESUMO

The reintroduction of dengue virus type 3 (DENV-3) in Brazil in 2000 and its subsequent spread throughout the country was associated with genotype III viruses, the only DENV-3 genotype isolated in Brazil prior to 2002. We report here the co-circulation of two different DENV-3 genotypes in patients living in the Northern region of Brazil during the 2002-2004 epidemics. Complete genomic sequences of viral RNA were determined from these epidemics, and viruses belonging to genotypes V (Southeast Asia/South Pacific) and III were identified. This recent co-circulation of different DENV-3 genotypes in South America may have implications for pathological and epidemiological dynamics.

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