Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni
AUTOR(ES)
Beck, Lílian, Van-Lüme, Daniele SM, Souza, Joelma R de, Morais, Clarice N Lins de, Melo, Wlademir G, Xavier, Edeneide, Barbosa, Constança S, Aroucha, Marcílio L, Domingues, Ana Lúcia C, Favre, Tereza, Pieri, Otávio, Abath, Frederico GC, Montenegro, Silvia ML
FONTE
Memórias do Instituto Oswaldo Cruz
DATA DE PUBLICAÇÃO
2004-08
RESUMO
Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.
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