Endotoxemia prevention by virginiamicyn administration in horses to starch overload / Prevenção da endotoxemia pela administração de virginiamicina em eqüinos submetidos à sobrecarga por amido

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

This work aimed to verify the administration of virginiamicyn in starch overload horses to control the harmful effects of this overload. This work was carried out in Universidade Federal Rural do Rio de Janeiro and consists of experimental starch overload by administration of corn starch at 17, 6 g/kg by a nasogastric probe. It was used 4 horses with a right ventral colon canula with four treatments in a latin square 4 x 4. T1 control, without virginiamicyn administration; T2 - virginiamicyn administration at same time of corn starch; T3 virginiamicyn administration 12 hours after corn starch; T4 - virginiamicyn administration at same time of corn starch and 12 hours after it. Clinical examinations and blood samples were colleted before the assay (zero time), 12, 24, 36 and 48 hours after carbohydrate overload. Besides the clinical evaluation, the endotoxin serum levels, the specific leukocyte counts and glycemia values of horses were determinate. There werent observed changes on mucosa color and refill time on treatments that virginiamicyn were administered in overload moment. Neither glycemia, nor specific and global leukocyte counts showed significant changes. Treatments used werent able to block the increase hooves temperature and digital pulse, in different levels in the horses. In other words, preventive supply of virginiamicyn at the overload moment, showed to be able to minimize the harmful effects caused by the carbohydrate overload. Better effects seem to be promoted by the virginiamicyn administration at same time and 12 hours after overload of corn starch, suggesting that sequential administration virginiamicyn is more efficient on hindgut acidosis control.

ASSUNTO(S)

medicina veterinaria terapêutica endotoxin cólica virginiamicyn equine antibiótico ionóforo.

ACESSO AO ARTIGO

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