Emergence of bla NDM-1 associated with the aac(6’)-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil

AUTOR(ES)

Scavuzzi, Alexsandra Maria Lima

FONTE

Rev. Soc. Bras. Med. Trop.

DATA DE PUBLICAÇÃO

16/05/2019

RESUMO

Abstract INTRODUCTION: The emergence of New Delhi metallo-β-lactamase (NDM) is concernig because it reduces the antibiotic therapy options for bacterial infections. METHODS: Resistant and virulent genes from an isolate of Klebsiella pneumoniae derived from a patient with sepsis in a hospital in Recife-PE, Brazil, were investigated using PCR and DNA sequencing. RESULTS: bla NDM-1, aac(6’)-Ib-cr and acrB resistance genes, and cps and mrkD virulence genes were detected. CONCLUSIONS To our knowledge, this is the first report on bla NDM-1 in Recife-PE. This detection alerts researchers to the need to control the spread of bla NDM-1 resistance gene by this bacterium in Brazil.

Documentos Relacionados

• Prevalência dos genes qnr, aac (6)Ib-cr e qepA entre isolados clínicos de enterobactérias.
• Second Acriflavine Sensitivity Mutation, acrB, in Escherichia coli K-12
• Perfil socioepidemiológico e autonomia de longevos em Recife-PE, Nordeste do Brasil
• Condições de trabalho e morbidade referida de policiais militares, Recife-PE, Brasil
• Excesso de peso e alguns fatores associados em escolares do Recife-PE, 2007