Effects of Trifolium pratense in menopausal symptoms and sexual satisfaction in climacteric women / Efeitos do Trifolium pratense nos sintomas da menopausa e na satisfação sexual em mulheres climatéricas

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

Objective: to evaluate the effects of Trifolium pratense treatment on the climacteric symptoms and sexualiy in postmenopausal women through Kuppermann Menopausal Index (KMI) and the Golombok Rust Inventory of Sexual Satisfaction (GRISS), respectively. Methods: This study was prospective, randomized, double-blind and placebo-controlled study. Hundred women were selected, aged between 45 and 65 years with climacteric symptoms, with menstruation absence (amenorrhea) that was more then one year and without any treatment for last six months. After selection, women were divided into two groups: GI (n = 50) received 40 mg Trifolium pratense (one capsule per day); GII (n = 50) received placebo (control, one capsule of lactose per day). The length of treatment was 12 months and women were evaluated before and after four, eight and twelve months of treatment through clinical and laboratorial exams. The t Student test and ANOVA were applied for analyzing the differences between groups. Results: There was significant ameliorate in the symptoms after four months of treatment through the KMI, mainly in hot flashes, compared to baseline data of both groups. The sexuality evaluation did not found any difference before and after treatment in both groups. Conclusion: Our data suggested that the 40 mg Trifolium pratense effect may be not superior than placebo in relation to decrease the postmenopausal symptoms during one year of study

ASSUNTO(S)

sexuality kuppermann menopausal index trifolium pratense sexualidade Índice menopausal de kupperman menopause isoflavonas trifolium pratense menopausa isoflavones

ACESSO AO ARTIGO

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