Effects of proportional assist ventilation on exercise capacity in idiopathic pulmonary fibrosis patients / Efeito da ventilação assistida proporcional na capacidade ao exercício em pacientes com fibrose pulmonar idiopática

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

The objective of the present study was to evaluate the effect of ventilatory support using proportional assist ventilation (PAV) on exercise capacity in patients with idiopathic pulmonary fibrosis. Ten patients were submitted to a cardiopulmonary exercise testing, lung function and 3 submaximal exercise tests (60% of maximum load): without ventilatory support, with continuous positive airway pressure (CPAP) and PAV. Exercise capacity, cardiovascular and ventilatory adaptations and subjective perception to effort in lower limb and respiratory breathing were evaluated. Lactate plasmatic levels were obtained before and after submaximal exercise. Our results show that submaximal exercise capacity duration was increased with PAV compared with CPAP and without ventilatory support. (respectively, 11.10±8.88 min, 5.60±4.74 e 4.50±3.84 min). Ventilatory support with PAV lead to a lower cardiovascular demand such as double product and heart rate decreased. An improved arterial oxygenation and lower subjective perception to effort was also observed in patients with IPF when exercise was performed with PAV. Our results suggest that ventilatory support with PAV can increase exercise tolerance and decrease dyspnea in patients with idiopathic pulmonary fibrosis.

ASSUNTO(S)

respiração artificial fibrose pulmonar pulmonary fibrosis tolerância ao exercício exercise tolerance pletismografia. respiração com pressão positiva dispnéia interstitial lung diseases exercise exercise test plethysmography. positive pressure respiration artificial respiration doenças pulmonares intersticiais dyspnea exercício teste de esforço

ACESSO AO ARTIGO

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