Effect of Clostridium perfringens epsilon toxin on the cardiovascular system of rats.
AUTOR(ES)
Sakurai, J
RESUMO
Pressor activity was demonstrated by the intravenous injection of purified epsilon toxin of Clostridium perfringens type D but not by that of epsilon prototoxin. The activity was completely abolished by C. perfringens type B or D antiserum, but not by type A, C, or E antiserum. The rise in blood pressure caused by the toxin was accompanied by a decrease in the blood flow in skin without any change of heart rate and electrocardiogram readings. These results indicate that epsilon toxin possesses pressor activity as well as lethal and dermonecrotic activities.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=264423Documentos Relacionados
- Tryptophan content of Clostridium perfringens epsilon toxin.
- Neurotoxicity of Clostridium perfringens Epsilon-Toxin for the Rat Hippocampus via the Glutamatergic System
- Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
- High-affinity binding of Clostridium perfringens epsilon-toxin to rat brain.
- Naturally acquired antibodies against Clostridium perfringens epsilon toxin in goats.