Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin

AUTOR(ES)

Alves, Guilherme Guerra, Machado-de-Ávila, Ricardo Andrez, Chávez-Olórtegui, Carlos Delfin, Silva, Rodrigo Otávio Silveira, Lobato, Francisco Carlos Faria

FONTE

Braz. J. Microbiol.

DATA DE PUBLICAÇÃO

2017-07

RESUMO

Abstract The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.

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