CorrelaÃÃo de elementos traÃo, densidade mineral Ãssea, massa livre de gordura e massa gorda em idosas

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

The trace elements in the organisms are responsible for innumerable functions, however, alterations in its concentrations can be associated with osteoporosis and sarcopenia, mainly in elderly women. Therefore, the current study had as aim to correlate trace elements with BMD, lean mass and fat mass in elderly women, monitored through hair exams. Twenty-seven volunteer elderly women (65.70 + 3.96 years old) were selected to take part in the study. The BMD from the femur neck, Wardâs triangle, trochanter and lumbar spine (L2-L4) was measured through Dual energy x-ray absortiometry (DXA) method. The concentrations of 31 elements: Ag, Al, As, B, Ba, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Li, Mg, Mn, Mo, Na, Ni, Pb, Sb, Sc, Se, Sn, Sr, Ti, V, Y, Zn, and Zr in the hair were determined through induced argon plasma-atomic emission spectrometry (ICP-OES) and atomic mass spectrometry (ICP-MS). Pearsonâs correlation and non-parametric coefficients: Spearmanâs and Kendallâs were used to identify possible inter-relations between the variables. The hierarchical cluster analysis was used to identify groups of similar cases. With the classification of two groups, an analysis of variance (ANOVA) was performed in order to identify the trace elements that presented mean difference between them. The trace elements with difference were Ag, Sn, Ca, K, Na, Mo, Sb, Se, Ti, B, Cu, Mg and Pb. In order to select variables which could explain the difference found on the means, a principal component analysis was performed. Among the elements with difference, Se and Pb presented high levels in the group with lower BMD. The analysis of hierarchical classification was also used to identify groups of similar cases between lean mass and fat mass. Beginning with the formation of two groups, an analysis of variance (ANOVA) was performed in order to identify the trace elements which showed mean difference in the groups with higher and lower lean mass and fat mass. In relation to body composition, the elements which showed difference were: Mo and Fe, in the group with higher lean mass and fat mass and Ba, Be, Na, and Ni, in the group with lower lean mass and fat mass. Data revealed the influence of the trace elements in BMD and in body composition. The results suggest that an unbalance in homeostasis of the trace elements on the organism is a risk factor for the reduction of BMD, possibly leading to osteoporosis. Lean mass and fat mass suffer the influence of the retention of trace elements in the organism. Therefore, hair analysis may eventually be a method of diagnosis for chronic diseases.

ASSUNTO(S)

hair osteoporosis cabelo massa gorda lean mass educacao fisica envelhecimento; osteoporose; idosos; elementos traÃos massa livre de gordura aging trace elements fat mass

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