Comparison of two automated instrument systems for rapid susceptibility testing of gram-negative bacilli.
AUTOR(ES)
Johnson, J E
RESUMO
The Vitek AutoMicrobic System with GSC-plus cards and the Abbott MS-2 system were tested in parallel and the results were compared directly with those of a reference microdilution minimal inhibitory concentration (MIC) procedure on a group of 262 clinical isolates of the family Enterobacteriaceae and of Pseudomonas aeruginosa. Results of both systems were compared with the reference MIC for category agreement, and in addition, the Vitek MICs were compared with those obtained by the reference procedure. The Vitek system provided an essential category correlation of 89.4% for enteric bacteria and 97.0% for P. aeruginosa. Vitek MICs agreed within 1 twofold dilutional increment for 86.3% of the enteric bacteria tested and for 96.2% of the P. aeruginosa isolates. The Abbott MS-2 essential categoric agreement was 92.0% for enteric bacteria and 92.4% for P. aeruginosa. If only aminoglycosides or carbenicillin were considered for P. aeruginosa isolates, the essential category agreement was 92.5% for the Vitek and 93.3% for the MS-2. The majority of MS-2 category errors (13 of 19) with P. aeruginosa involved gentamicin results on isolates whose reference MICs were 8 micrograms/ml and whose MS-2 results were susceptible (MIC less than or equal to 4 micrograms/ml). Retesting of the P. aeruginosa isolates in calcium-supplemented MS-2 broth increased the essential agreement for the aminoglycosides to 97.5%.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=272897Documentos Relacionados
- Comparison of Two Automated Instrument Systems for Rapid Susceptibility Testing of Gram-Negative Bacilli
- Comparison of three automated systems for antimicrobial susceptibility testing of gram-negative bacilli.
- Evaluation of the Autoscan Walkaway system for rapid identification and susceptibility testing of gram-negative bacilli.
- Evaluation of the AutoMicrobic system for identification and susceptibility testing of gram-negative bacilli.
- Evaluation of the AutoMicrobic system for susceptibility testing of aminoglycosides and gram-negative bacilli.