Comparison of a laboratory and a production coating spray gun with respect to scale-up
AUTOR(ES)
Mueller, Ronny
FONTE
Springer-Verlag
RESUMO
A laboratory spray gun and a production spray gun were investigated in a scale-up study. Two Schlick spray guns, which are equipped with a new antibearding cap, were used in this study. The influence of the atomization air pressure, spray gun-to tablet bed distance, polymer solution viscosity, and spray rate were analyzed in a statistical design of experiments. The 2 spray guns were compared with respect to the spray width and height, droplet size, droplet velocity, and spray density. The droplet size, velocity, and spray density were measured with a Phase Doppler Particle Analyzer.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2750438Documentos Relacionados
- Scale-up of a pan-coating process
- Scale-up of Heat Sterilization Operations1
- Scale-up of dextransucrase production by Leuconostoc mesenteroides in fed batch fermentation
- Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system
- Production of inulinase: recovery and scale-up