Capacidade física e o metaborreflexo em pacientes obesos mórbidos com síndrome da apneia obstrutiva do sono / Physical capacity and metaborreflex of peripheral muscle in morbidy obese patients with syndrome of obstructive sleep apnea

AUTOR(ES)

Winston Isio Boff Pereira de Souza

DATA DE PUBLICAÇÃO

2008

RESUMO

Previous studies have shown that obese individuals with syndrome of obstructive sleep apnea (OSA) present attenuated skeletal muscle metaborreflex. Muscle blood flow (MBF) evaluated by venous occlusion plethysmography has been used as marker of neurovascular control. In the present study, exercise capacity was measured by the distance performed in the six-minute walk test (6mWT), and heart rate (HR) was measured during this procedure. Paired t test, analysis of variance (ANOVA) for repeated measures, and Pearson correlation test were used to statistical analyses, and P<0.05 was assumed as statistically significant. We studied 13 obese individuals aged 26.4 5.8 years (Mean standard error), including 9 men and 4 women, with body mass index of 56 6.4 kg/m2. Mean apnea during the sleep was 34.11 8.3 AH / h without drug treatment. There was no correlation between muscle metaborreflex and 6mWT. Compared to baseline, there were significant changes in MBF and forearm vascular resistance during metaborreflex induction (by vascular occlusion 3 minutes after handgrip exercise), but not during the control condition (no occlusion after handgrip exercise). Forearm vascular resistance was increased during metaborreflex induction. There was no correlation between muscle metaborreflex and performed distance in 6MWT. In conclusion, obese subjects with OSA.

ASSUNTO(S)

obesidade mórbida metaborreflex capacity physics capacidade física apneia obstrutiva do sono obstructive sleep apnea metaborreflexo educacao fisica obesity morbid

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