AvaliaÃÃo da manometria esofÃgica em portadores de esquistossomose mansÃnica com varizes de esÃfago

AUTOR(ES)
DATA DE PUBLICAÇÃO

2004

RESUMO

Schistosomiasis mansoni is an infectious disease, caused by a worm (Schistosoma mansoni) trematode, family Schistosomatidae, genus Schistosoma, which principal characteristic is the sexual dismorfism when adult. The man is the principal host. The transmition of the disease is dependent on the presense of intermediary host, which in Brasil are the snail of gender Biomphalaria. The massive embolization by eggs layed in the portal venous sistems by adult forms of the parasite causes inflammatory reactions in the liver, modifying the architecture with formation of granulomas. The action of Schistossoma determines an imunological reaction in the liver and in the spleen, this hyperplasia of endotelial system wich increase of spleenâs volum results in a portal overflow. The increase of portal blood flow in association with pre-sinusoidal block result in hypertension in the site of distal esophagus and gastric fundus. The great clinical representation of portal hypertension is the development of varicose veins of esophagus. The rupture of varicose veins is the principal etiology of dead in the patients with schistosomiasis mansoni. Clinical assays have showed signals of increase in gastric-esophagical reflux and complains in larynx by patients with schistosomiasis mansoni and still there are doubts if this increase of reflux is related with motors disturbs os esophagus. The goals of this research were to value the behavior of low sphincter of esophagus and the esophagus body in patients with schistosomiasis mansoni and varicose veins in esophagus. Two groups were made. The A group (group of schistosomiasis mansoni) with 26 patients of schistosomiasis mansoni, in the advanced stages and with history of episodes of upper digestive bleedings in attendance in outpatient. This patients were submited to clinical avaliation, laboratorial avaliation, ultra-sonography, endoscopy, and manometry. The B group (Control group) with 24 healthy volunteers, without complains or history of episodes of upper digestive bleedings, this volunteers were submited to clinical avaliation, ultra-sonography, and manometry. The manometry exam was made with a system of manometry in solid state conected to a personal computer. The software called Monograph 3.1.1.1. was responsable for process the informations. The results were submited to Student t test. The author conclude that the pression of lower sphincter of esophagus and the pressions of the body of esophagus during the wet swallows in the patients with schistosomiasis mansoni and varicose veins in esophagus were statisticaly lower when compared with the control group. When was valueded the relaxion pression of lower sphinter of esophagus there wasnÂt difference between the groups

ASSUNTO(S)

portal hypertension cirurgia esophagus manometry esquistossomsoe mansÃnica hipertensÃo portal schistosomiasis mansoni manometria esofÃgica

ACESSO AO ARTIGO

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