Automatic hippocampus segmentation through similarity cloud / Segmentação da estrutura cerebral hipocampo por meio de nuvem de similaridade

AUTOR(ES)

Fredy Edgar Carranza Athó

FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

03/08/2011

RESUMO

The hippocampus is a particular structure that plays a main role in human memory systems. Tissue modifications of the hippocampus lead to neurodegenerative diseases as epilepsy, multiple sclerosis, and dementia, among others. To measure hippocampus atrophy, it is crucial to get its isolated representation from the whole brain volume. Separating the hippocampus from the brain helps physicians in better analyzing and understanding its volume reduction, and detecting any abnormal behavior. The extraction of the hippocampus is dominated by manual segmentation, which is time consuming mainly because it depends on user interaction. Therefore, automatic segmentation of the hippocampus has being investigated as an alternative solution to overcome such limitations. This master dissertation presents a new automatic segmentation method called Similarity Cloud Model (SimCM) based on hippocampus feature extraction. The segmentation process consists of two main operations: i) localization by similarity, and ii) cloud adjustment. The first operation uses the cloud to localize the most probable position of the hippocampus in a target volume. The second process invokes the cloud to correct the final labeling, based on a new method for arc-weight re-adjustment. Our method has been tested in a dataset of 235 MRIs combining healthy and epileptic patients. Results indicate superior performance, in terms of effectiveness (segmentation quality) and efficiency (processing time), in comparison with similar graph-based and Bayesian-based models. As future work, we intend to use feature selection to improve cloud construction and tissue delineation

ASSUNTO(S)

consultas por similaridade image forest-transforms modelos de nuvens transformada imagem floresta automatica hippocampus segmentation cloud mode content-based image retrieval recuperação de imagens por conteúdo segmentação automática do hipocampo similarity queries

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