Antimalarial Activities of Polyhydroxyphenyl and Hydroxamic Acid Derivatives
AUTOR(ES)
Holland, Kevin P.
FONTE
American Society for Microbiology
RESUMO
Several known mammalian ribonucleotide reductase inhibitors featuring a polyhydroxyphenyl and/or hydroxamate moiety as the active group were screened for potency in inhibiting growth of the malaria parasite Plasmodium falciparum. Compounds containing a 2,3- or 3,4-dihydroxyphenyl group as well as benzohydroxamate appear to be the most effective inhibitors of the malaria parasite.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105855Documentos Relacionados
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