Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
AUTOR(ES)
Azevedo, Ítalo Medeiros, Carvalho, Marília Daniela Ferreira, Nascimento, Rafael Pereira, Macedo, Robson, Aquino, Mônica Raquel de Souza, Medeiros, Aldo Cunha
FONTE
Acta Cir. Bras.
DATA DE PUBLICAÇÃO
2017-03
RESUMO
Abstract Purpose: To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model. Methods: Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal puncture. Micro-PET Images from abdominal cavity septic foci were obtained using 18-Fluoro-deoxyglucose, looking for a correlation with photographic images of abdominal cavity organs. Pearson's correlation test was used. Results: The mean standard uptake values (SUV) and lesion areas were 2.58±0.63SUVbwg/ml and 546.87±300.95mm2, respectively. There was a strong positive correlation between the two variables (r=0.863, p=0.137), which resulted in a coefficient of determination r2?0.75, meaning that 75% of SUV variation is explained by the lesion areas of digestive organs. Conclusion: Micro-PET allows high throughput assessment of lesion count and volume in pre-clinical rat model of CPL abdominal sepsis.
Documentos Relacionados
- FDG‐PET in meningeal lymphomatosis
- Comparative study of reliability of inflammatory markers over 18-FDG−PET CT scan in monitoring skull base osteomyelitis
- Risk Assessment Based on FDG-PET Imaging in Patients with Synovial Sarcoma
- More on the Timing and Meaning of FDG-PET Abnormalities in Partial Epilepsy
- Hipometabolismo cerebral em pacientes com esclerose mesial temporal demonstrado pelo FDG-PET